肠道微生物群与肥胖：潜在治疗靶点及益生菌治疗
Gut Microbiota and Obesity: Potential Therapeutic Targets and Probiotic Treatment.
作者信息
White Nicole D
机构信息
Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska.
出版信息
Am J Lifestyle Med. 2015 Nov 24;10(2):104-106. doi: 10.1177/1559827615619586. eCollection 2016 Mar-Apr.
Abstract
The gut bacteria model attributes obesity to the variable makeup of gut microbiota and its ability to modulate host energy homeostasis, adiposity and inflammation. To counteract these deleterious effects, strains of probiotics have been developed to manipulate gut microbiomes and improve health. The current article explores the mechanisms by which gut microbiota modulate host metabolism and highlights recent human study data assessing the effects of probiotic supplementation on the prevention and treatment of obesity.
摘要
肠道细菌模型将肥胖归因于肠道微生物群的可变组成及其调节宿主能量稳态、肥胖和炎症的能力。为了抵消这些有害影响，已开发出益生菌菌株来操纵肠道微生物群并改善健康状况。本文探讨了肠道微生物群调节宿主代谢的机制，并重点介绍了评估补充益生菌对肥胖预防和治疗效果的最新人体研究数据。
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