Suppr超能文献

肥胖症:趋同与分歧范式概述

The Obesities: An Overview of Convergent and Divergent Paradigms.

作者信息

Karasu Sylvia R

机构信息

Weill Cornell Medical College, New York, New York.

出版信息

Am J Lifestyle Med. 2014 Jul 4;10(2):84-96. doi: 10.1177/1559827614537773. eCollection 2016 Mar-Apr.

Abstract

The study of obesity lends itself to difficulties not only due to our imprecise ability to measure body composition, food consumption, and physical activity but also, even more important, due to complexities involved in defining and conceptualizing obesity. For centuries, obesity has been considered a disease, although researchers and clinicians cannot agree on definitions of "disease" or, if it is one, whether obesity is a disease of metabolism, inflammation, brown fat, chronobiology, the blood-brain barrier, the right brain, or even of infectious origin. The concept of "obesity" as a disease remains controversial to some because not everyone who has excess adipose tissue has any evidence of disease. Obesity, though, has also been considered a sin, a crime against society, an aesthetic crime, a self-inflicted disability, an example of body diversity, a failure in the regulation of energy balance, an appropriate or even inappropriate adaptation to our increasingly obesogenic environment, a genetic disorder, and a psychological/behavioral disorder of overeating involving self-regulation or even addiction. Five major paradigms-medical, sociocultural, evolutionary, environmental, and psychological/behavioral, all with their own subcategorical models-have been identified. All 5 paradigms are required because we are dealing not with "obesity" but with a plurality, the "obesities."

摘要

肥胖研究面临诸多困难,这不仅是因为我们在测量身体成分、食物摄入量和身体活动方面能力不够精确,更重要的是,在定义和概念化肥胖时存在复杂性。几个世纪以来,肥胖一直被视为一种疾病,尽管研究人员和临床医生对于“疾病”的定义无法达成一致,也不确定如果肥胖是一种疾病,它是代谢性疾病、炎症性疾病、棕色脂肪疾病、生物钟学疾病、血脑屏障疾病、右脑疾病,甚至是传染性疾病。“肥胖”作为一种疾病的概念在一些人看来仍然存在争议,因为并非每个脂肪组织过多的人都有疾病迹象。然而,肥胖也被视为一种罪恶、一种对社会的犯罪、一种审美犯罪、一种自我造成的残疾、身体多样性的一个例子、能量平衡调节失败、对我们日益肥胖的环境的一种适当甚至不适当的适应、一种遗传疾病,以及一种涉及自我调节甚至成瘾的暴饮暴食的心理/行为障碍。已经确定了五个主要范式——医学、社会文化、进化、环境和心理/行为范式,每个范式都有自己的子分类模型。所有这五种范式都是必需的,因为我们面对的不是“肥胖”,而是多种“肥胖症”。

相似文献

1
The Obesities: An Overview of Convergent and Divergent Paradigms.
Am J Lifestyle Med. 2014 Jul 4;10(2):84-96. doi: 10.1177/1559827614537773. eCollection 2016 Mar-Apr.
2
The Obesities: Various Paradigms Addressing a Single Problem.
Am J Lifestyle Med. 2016 Mar 16;10(2):97-99. doi: 10.1177/1559827615618877. eCollection 2016 Mar-Apr.
4
Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012).
Phys Biol. 2013 Aug;10(4):040301. doi: 10.1088/1478-3975/10/4/040301. Epub 2013 Aug 2.
5
[From obesity to obesities: from concepts to practices].
Ann Endocrinol (Paris). 2003 Nov;64(5 Pt 2):S7-15.
6
Of mind and matter: psychological dimensions in obesity.
Am J Psychother. 2012;66(2):111-28. doi: 10.1176/appi.psychotherapy.2012.66.2.111.
7
Translational Pharmacology and Physiology of Brown Adipose Tissue in Human Disease and Treatment.
Handb Exp Pharmacol. 2019;251:381-424. doi: 10.1007/164_2018_184.
8
9
Obesity, obesities and gastrointestinal cancers.
Dis Mon. 2023 Dec;69(12):101592. doi: 10.1016/j.disamonth.2023.101592. Epub 2023 Jun 10.
10
The evolution of human fatness and susceptibility to obesity: an ethological approach.
Biol Rev Camb Philos Soc. 2006 May;81(2):183-205. doi: 10.1017/S1464793105006974.

引用本文的文献

2
Efficacy of a Universal Weight Stigma Intervention on the Quality of Parent-Child Conversations About Weight.
J Adolesc Health. 2025 Apr;76(4):680-689. doi: 10.1016/j.jadohealth.2024.11.012. Epub 2025 Feb 2.
3
Creativity in energy balance, obesity and feeding behavior research, some thoughts.
Physiol Behav. 2023 Jul 1;266:114161. doi: 10.1016/j.physbeh.2023.114161. Epub 2023 Mar 21.
4
Disrupting Essentialism in Medical Genetics Education.
Med Sci Educ. 2021 Nov 15;32(1):255-262. doi: 10.1007/s40670-021-01458-w. eCollection 2022 Feb.
5
Gut Microbiota and Obesity: Potential Therapeutic Targets and Probiotic Treatment.
Am J Lifestyle Med. 2015 Nov 24;10(2):104-106. doi: 10.1177/1559827615619586. eCollection 2016 Mar-Apr.
6
Bridging the Science-Practice Gap in Obesity Treatment.
Am J Lifestyle Med. 2015 Dec 15;10(2):100-103. doi: 10.1177/1559827615620381. eCollection 2016 Mar-Apr.

本文引用的文献

1
Obesity, Complexity, and the Role of the Health System.
Curr Obes Rep. 2013 Aug 30;2(4):320-326. doi: 10.1007/s13679-013-0072-9. eCollection 2013.
2
Food addiction: its prevalence and significant association with obesity in the general population.
PLoS One. 2013 Sep 4;8(9):e74832. doi: 10.1371/journal.pone.0074832. eCollection 2013.
3
Gut microbiota from twins discordant for obesity modulate metabolism in mice.
Science. 2013 Sep 6;341(6150):1241214. doi: 10.1126/science.1241214.
4
Evolutionary perspectives on the obesity epidemic: adaptive, maladaptive, and neutral viewpoints.
Annu Rev Nutr. 2013;33:289-317. doi: 10.1146/annurev-nutr-071811-150711.
5
Addressing the wicked problem of obesity through planning and policies.
PLoS Med. 2013;10(6):e1001475. doi: 10.1371/journal.pmed.1001475. Epub 2013 Jun 25.
6
Scientific decision making, policy decisions, and the obesity pandemic.
Mayo Clin Proc. 2013 Jun;88(6):593-604. doi: 10.1016/j.mayocp.2013.04.005.
7
Chronobiological Effects on Obesity.
Curr Obes Rep. 2012 Mar 1;1(1):9-15. doi: 10.1007/s13679-011-0005-4.
8
Standards and classification: a perspective on the 'obesity epidemic'.
Soc Sci Med. 2013 Jun;87:9-15. doi: 10.1016/j.socscimed.2013.03.009. Epub 2013 Mar 18.
9
Evidence for obesogens: interpretations and next steps.
Obesity (Silver Spring). 2013 Jun;21(6):1077-8. doi: 10.1002/oby.20475.
10
An integrated approach to assess the role of chemical exposure in obesity.
Obesity (Silver Spring). 2013 Jun;21(6):1084-5. doi: 10.1002/oby.20478.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验