Karasu Sylvia R
Weill Cornell Medical College, New York, New York.
Am J Lifestyle Med. 2014 Jul 4;10(2):84-96. doi: 10.1177/1559827614537773. eCollection 2016 Mar-Apr.
The study of obesity lends itself to difficulties not only due to our imprecise ability to measure body composition, food consumption, and physical activity but also, even more important, due to complexities involved in defining and conceptualizing obesity. For centuries, obesity has been considered a disease, although researchers and clinicians cannot agree on definitions of "disease" or, if it is one, whether obesity is a disease of metabolism, inflammation, brown fat, chronobiology, the blood-brain barrier, the right brain, or even of infectious origin. The concept of "obesity" as a disease remains controversial to some because not everyone who has excess adipose tissue has any evidence of disease. Obesity, though, has also been considered a sin, a crime against society, an aesthetic crime, a self-inflicted disability, an example of body diversity, a failure in the regulation of energy balance, an appropriate or even inappropriate adaptation to our increasingly obesogenic environment, a genetic disorder, and a psychological/behavioral disorder of overeating involving self-regulation or even addiction. Five major paradigms-medical, sociocultural, evolutionary, environmental, and psychological/behavioral, all with their own subcategorical models-have been identified. All 5 paradigms are required because we are dealing not with "obesity" but with a plurality, the "obesities."
肥胖研究面临诸多困难,这不仅是因为我们在测量身体成分、食物摄入量和身体活动方面能力不够精确,更重要的是,在定义和概念化肥胖时存在复杂性。几个世纪以来,肥胖一直被视为一种疾病,尽管研究人员和临床医生对于“疾病”的定义无法达成一致,也不确定如果肥胖是一种疾病,它是代谢性疾病、炎症性疾病、棕色脂肪疾病、生物钟学疾病、血脑屏障疾病、右脑疾病,甚至是传染性疾病。“肥胖”作为一种疾病的概念在一些人看来仍然存在争议,因为并非每个脂肪组织过多的人都有疾病迹象。然而,肥胖也被视为一种罪恶、一种对社会的犯罪、一种审美犯罪、一种自我造成的残疾、身体多样性的一个例子、能量平衡调节失败、对我们日益肥胖的环境的一种适当甚至不适当的适应、一种遗传疾病,以及一种涉及自我调节甚至成瘾的暴饮暴食的心理/行为障碍。已经确定了五个主要范式——医学、社会文化、进化、环境和心理/行为范式,每个范式都有自己的子分类模型。所有这五种范式都是必需的,因为我们面对的不是“肥胖”,而是多种“肥胖症”。