O'Reilly Sean
Pulmonary, Critical Care, and Sleep Medicine, Sentara Martha Jefferson Medical Group, Sentara Martha Jefferson Hospital, Charlottesville, Virginia.
Am J Lifestyle Med. 2016 Jul 7;11(4):296-302. doi: 10.1177/1559827616656593. eCollection 2017 Jul-Aug.
COPD is a common, preventable, and treatable disease characterized by persistent airflow obstruction associated with enhanced inflammation in the airways and the lung in response to noxious particles or gases. Clinical history and pulmonary function testing are necessary for accurate diagnosis. While exposure to tobacco smoke remains a common cause, other etiologies and underlying genetic predisposition play significant roles. Treatment options are numerous and should be individualized based on symptoms and exacerbation frequency.
慢性阻塞性肺疾病(COPD)是一种常见、可预防且可治疗的疾病,其特征为持续气流受限,伴有气道和肺部对有害颗粒或气体的炎症反应增强。准确诊断需要临床病史和肺功能测试。虽然接触烟草烟雾仍是常见病因,但其他病因和潜在的遗传易感性也起着重要作用。治疗选择众多,应根据症状和急性加重频率进行个体化治疗。