Arena Ross, Lavie Carl J, Guazzi Marco
Department of Physical Therapy and Integrative Physiology Laboratory, College of Applied Science, University of Illinois at Chicago, Chicago, Illinois (RA).
Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-The University of Queensland School of Medicine, New Orleans, Louisiana (CJL).
Am J Lifestyle Med. 2015 Nov 30;11(6):476-478. doi: 10.1177/1559827615619341. eCollection 2017 Nov-Dec.
The paradigm allowing for a lifestyle immersed in unhealthy behaviors to perpetuate to a point where a non-communicable disease (NCD) is eminent or manifests, and then initiating health care interventions, is deeply flawed, results in poor outcomes, and is unsustainable. This paradigm describes the current predominant healthcare model in many countries around the world and has resulted in the continual increase in unhealthy lifestyle patterns that have led to the global NCD epidemic. It is now broadly recognized that rapid integration of a new healthcare model, one heavily focused on primordial and primary NCD prevention, is needed. Being physically active, eating healthy and nutritious foods, not smoking and minimizing second-hand exposure, and maintaining an appropriate body weight are central to this new prevention model. Combined, these four characteristics can be viewed as the key ingredients for the "healthy lifestyle polypill". Recently, the American Heart Association (AHA), European Society of Cardiology (ESC), European Association for Cardiovascular Prevention and Rehabilitation (EACPR), and American College of Preventive Medicine (ACPM) came together to publish, in both the , a policy statement entitled "Healthy Lifestyle Interventions to Combat Non-Communicable Disease: A Novel Non-Hierarchical Connectivity Model for Key Stakeholders". We hope the AHA-ESC-EACPR-ACPM healthy lifestyle policy statement prompts a massive increase in production of the healthy lifestyle polypill. Regulatory approval is not needed to start manufacturing and distributing this medication. The polypill can take many forms and have differing ingredients and dosages while still maintaining high therapeutic efficacy.
允许沉浸于不健康行为的生活方式持续到非传染性疾病（NCD）显著或显现出来，然后才启动医疗保健干预措施的这种模式存在严重缺陷，会导致不良后果，且不可持续。这种模式描述了当今世界许多国家占主导地位的医疗保健模式，并导致了不健康生活方式模式的持续增加，进而引发了全球非传染性疾病的流行。现在人们广泛认识到，需要迅速整合一种新的医疗保健模式，即高度注重非传染性疾病的初级预防和一级预防。积极锻炼身体、食用健康营养的食物、不吸烟并尽量减少二手烟暴露以及保持适当体重是这种新预防模式的核心。综合起来，这四个特征可被视为 “健康生活方式多效药丸” 的关键要素。最近，美国心脏协会（AHA）、欧洲心脏病学会（ESC）、欧洲心血管预防与康复协会（EACPR）和美国预防医学学院（ACPM）共同在《》上发表了一份政策声明，题为 “对抗非传染性疾病的健康生活方式干预措施：一种面向关键利益相关者的新型非等级连接模式”。我们希望AHA - ESC - EACPR - ACPM的健康生活方式政策声明能促使健康生活方式多效药丸的产量大幅增加。开始生产和分发这种药物无需监管批准。多效药丸可以有多种形式，成分和剂量也各不相同，但仍能保持较高的治疗效果。
