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B淋巴细胞同种抗原

B-lumphocyte alloantigens.

作者信息

Johnson A H, Ward F E, Amos D B

出版信息

Scand J Immunol. 1977;6(5):403-8. doi: 10.1111/j.1365-3083.1977.tb02095.x.

Abstract

Seventy B-cell alloantisera were tested by microcytotoxicity against a panel of B-cell-enriched and T-cell-enriched lymphocytes. Six groups were discerned and have tentatively been designated DIg 1-7 (for Duke immunoglobulin-positive cell groups). These alloantisera were used to type an HLA-A/B recombinant family. Two groups were observed to segregate in this family, DIg 7 with the HLA-B locus and DIg 2 with the HLA-A locus.

摘要

通过微量细胞毒性试验,使用70种B细胞同种抗血清检测一组富含B细胞和富含T细胞的淋巴细胞。识别出6个组,并暂时命名为DIg 1 - 7(代表杜克免疫球蛋白阳性细胞组)。这些同种抗血清用于对一个HLA - A/B重组家系进行分型。观察到该家系中有两个组发生分离,DIg 7与HLA - B位点连锁,DIg 2与HLA - A位点连锁。

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