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横行清创及急性缩短后行牵张组织再生术治疗伴有骨与软组织缺损的开放性胫骨骨折

Transverse debridement and acute shortening followed by distraction histogenesis in the treatment of open tibial fractures with bone and soft tissue loss.

作者信息

Salih Saif, Mills Edward, McGregor-Riley Jonathan, Dennison Mick, Royston Simon

机构信息

Trauma and Limb Reconstruction Unit, Department of Trauma and Orthopaedics, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK.

出版信息

Strategies Trauma Limb Reconstr. 2018 Nov;13(3):129-135. doi: 10.1007/s11751-018-0316-z. Epub 2018 Sep 11.

Abstract

This retrospective case series evaluates the technique of transverse debridement, acute shortening and subsequent distraction histogenesis in the management of open tibial fractures with bone and soft tissue loss, thereby avoiding the need for a soft tissue flap to cover the wound. Thirty-one patients with Gustilo grade III open tibial fractures between 2001 and 2011 were initially managed with transverse wound extensions, debridement and shortening to provide bony apposition and allowing primary wound closure without tension, or coverage with mobilization of soft tissue and split skin graft. Temporary monolateral external fixation was used to allow soft tissues resuscitation, followed by Ilizarov frame for definitive fracture stabilization. Leg length discrepancy was corrected by corticotomy and distraction histogenesis. Union was evaluated radiologically and clinically. Patients' mean age was 37.3 years (18.3-59.3). Mean bone defect was 3.2 cm (1-8 cm). Mean time to union was 40.1 weeks (12.6-80.7 weeks), and median frame index was 75 days/cm. Median lengthening index (time in frame after corticotomy for lengthening) was 63 days/cm. Mean clinic follow-up was 79 weeks (23-174). Six patients had a total of seven complications. Four patients re-fractured after frame removal, one of whom required a second frame. Two patients required a second frame for correction of residual deformity, and one patient developed a stiff non-union which united following a second frame. There were no cases of deep infection. Acute shortening followed by distraction histogenesis is a safe method for the acute treatment of open tibial fractures with bone and soft tissue loss. This method also avoids the cost, logistical issues and morbidity associated with the use of local or free-tissue transfer flaps and has a low rate of serious complications despite the injury severity.

摘要

本回顾性病例系列评估了横向清创、急性短缩及后续牵张组织生成技术在伴有骨与软组织缺损的开放性胫骨骨折治疗中的应用,从而避免了使用软组织瓣覆盖伤口的必要性。2001年至2011年间,31例GustiloⅢ级开放性胫骨骨折患者最初接受了横向伤口延长、清创及短缩治疗,以实现骨对合,并允许一期无张力伤口闭合,或通过软组织松动和分层皮片移植进行覆盖。采用临时单侧外固定以促进软组织复苏,随后使用Ilizarov架进行确定性骨折固定。通过截骨术和牵张组织生成纠正肢体长度差异。通过影像学和临床评估骨折愈合情况。患者平均年龄为37.3岁(18.3 - 59.3岁)。平均骨缺损为3.2厘米(1 - 8厘米)。平均愈合时间为40.1周(12.6 - 80.7周),平均外固定架指数为75天/厘米。平均截骨后延长指数(截骨后延长在外固定架内的时间)为63天/厘米。平均临床随访时间为79周(23 - 174周)。6例患者共出现7种并发症。4例患者在拆除外固定架后再次骨折,其中1例需要再次使用外固定架。2例患者需要再次使用外固定架以纠正残留畸形,1例患者出现僵硬性骨不连,在再次使用外固定架后实现愈合。无深部感染病例。急性短缩后进行牵张组织生成是治疗伴有骨与软组织缺损的开放性胫骨骨折的一种安全方法。该方法还避免了使用局部或游离组织转移瓣所带来的成本、后勤问题及发病率,尽管损伤严重,但严重并发症发生率较低。

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