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Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium.

作者信息

Horowitz S, Borcherding W, Moorthy A V, Chesney R, Schulte-Wisserman H, Hong R

出版信息

Science. 1977 Sep 2;197(4307):999-1001. doi: 10.1126/science.302032.

DOI:10.1126/science.302032
PMID:302032
Abstract

Patients with systemic lupus erythematosus lacked suppressor T cell function. Suppressor cell activity was induced in cells from many of these patients by incubation with thymosin or cultured thymic epithelium. These results suggest that thymic manipulation may be a useful therapeutic modality in this disease.

摘要

相似文献

1
Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium.
Science. 1977 Sep 2;197(4307):999-1001. doi: 10.1126/science.302032.
2
In vitro effect of thymosin on T-lymphocyte rosette formation in rheumatic diseases.胸腺素对风湿性疾病中T淋巴细胞玫瑰花结形成的体外作用。
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Thymosin From Bombyx mori Is Down-Regulated in Expression by BmNPV Exhibiting Antiviral Activity.家蚕胸腺素在表现出抗病毒活性的家蚕核型多角体病毒作用下表达下调。
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Lymphocyte dysfunction in congenital hypoplastic anemia.先天性再生障碍性贫血中的淋巴细胞功能障碍。
J Clin Invest. 1982 Sep;70(3):619-26. doi: 10.1172/jci110655.
3
Induction of T lymphocyte differentiation by thymic factors.胸腺因子诱导T淋巴细胞分化
Mol Cell Biochem. 1981 Dec 4;41:119-22. doi: 10.1007/BF00225302.
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Subpopulations of T lymphocytes in patients with ankylosing spondylitis.强直性脊柱炎患者的T淋巴细胞亚群
Ann Rheum Dis. 1980 Dec;39(6):566-9. doi: 10.1136/ard.39.6.566.
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Spontaneous plaque forming cells in the peripheral blood of patients with systemic lupus erythematosus.系统性红斑狼疮患者外周血中的自发斑块形成细胞
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Experimental autoimmune thyroiditis: modulation of the disease level in high and low responder mice by thymosin.实验性自身免疫性甲状腺炎:胸腺素对高反应性和低反应性小鼠疾病水平的调节
Clin Exp Immunol. 1984 Oct;58(1):83-9.
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Clin Exp Immunol. 1981 Jun;44(3):459-66.
8
Autoantibody to an immunoregulatory inducer population in patients with juvenile rheumatoid arthritis.青少年类风湿性关节炎患者体内针对免疫调节诱导细胞群体的自身抗体。
J Clin Invest. 1981 Mar;67(3):753-61. doi: 10.1172/JCI110092.
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Depressed suppressor cell activity in patients with newly diagnosed insulin-dependent diabetes mellitus.新诊断的胰岛素依赖型糖尿病患者中抑制性细胞活性降低。
Clin Exp Immunol. 1980 Jul;41(1):25-32.
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Depressed primary in vitro antibody response in untreated systemic lupus erythematosus. T helper cell defect and lack of defective suppressor cell function.未经治疗的系统性红斑狼疮患者体外抗体反应低下。辅助性T细胞缺陷且抑制性细胞功能无缺陷。
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