Horowitz S, Borcherding W, Moorthy A V, Chesney R, Schulte-Wisserman H, Hong R
Science. 1977 Sep 2;197(4307):999-1001. doi: 10.1126/science.302032.
Patients with systemic lupus erythematosus lacked suppressor T cell function. Suppressor cell activity was induced in cells from many of these patients by incubation with thymosin or cultured thymic epithelium. These results suggest that thymic manipulation may be a useful therapeutic modality in this disease.