老年女性膀胱过度活动症的管理
Management of Overactive Bladder in Older Women.
作者信息
Pratt Toya S, Suskind Anne M
机构信息
Kaiser Permanente East Bay-University of California San Francisco, 275 MacArthur Blvd, Oakland, CA, 94618, USA.
University of California, San Francisco, 400 Parnassus Avenue, Box 0738, San Francisco, CA, 94143, USA.
出版信息
Curr Urol Rep. 2018 Sep 10;19(11):92. doi: 10.1007/s11934-018-0845-5.
Abstract
PURPOSE OF REVIEW
This review will highlight our current understanding of age-related changes in bladder function and propose important clinical considerations in the management of overactive bladder (OAB) specific to older women.
RECENT FINDINGS
Frailty, functional and cognitive impairment, multimorbidity, polypharmacy, estrogen deficiency, and remaining life expectancy are important clinical factors to consider and may impact OAB symptom management in older women. Third-line therapies, particularly PTNS, may be preferable over second-line therapy in some cases. Due to the complexity within this population, the standard treatment algorithms may not be applicable, thus a broader, more holistic focus is recommended when managing OAB in older women.
摘要
综述目的
本综述将着重阐述我们目前对膀胱功能随年龄变化的理解，并提出针对老年女性膀胱过度活动症（OAB）管理的重要临床考量因素。
最新发现
虚弱、功能和认知障碍、多种疾病并存、多种药物治疗、雌激素缺乏以及剩余预期寿命是需要考虑的重要临床因素，可能会影响老年女性OAB症状的管理。在某些情况下，三线治疗，尤其是经皮胫神经刺激（PTNS）可能比二线治疗更可取。由于该人群情况复杂，标准治疗方案可能不适用，因此在管理老年女性OAB时，建议采用更广泛、更全面的方法。
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