Wuhan No.1 Hospital, Wuhan, China.
The School of Nursing, Anhui University of Chinese Medicine, Hefei, China.
Nurs Open. 2022 Jan;9(1):402-407. doi: 10.1002/nop2.1078. Epub 2021 Sep 25.
Some meta-analyses have proved the superiority of non-pharmacological interventions in overactive bladder (OAB), but the best choice is still controversial.
To assess the most effective interventions in female with OAB.
Studies for relevant randomized controlled trials which compare different kinds of non-pharmacological interventions in females with OAB will be retrieved from 8 databases including PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure, Wanfang Database, VIP Database and China Biology Medicine disc, from inception to 1 January 2021. After screening titles and abstracts, detailed data including participates, interventions and outcomes will be extracted according to the eligible criteria. Then, Cochrane risk-of-bias tool will be used to assess the quality of the literature. The pairwise meta-analysis will be conducted by STATA. Network meta-analysis will be performed to compare and rank the effects of different non-pharmacological interventions, in terms of alleviation of symptoms, by OpenBUGS, R and STATA.
This network meta-analysis will present the best available evidence about non-pharmacological interventions for OAB to both relieve symptoms and improve life quality.
一些荟萃分析已经证明了非药物干预在治疗膀胱过度活动症(OAB)方面的优势,但最佳选择仍存在争议。
评估女性 OAB 患者最有效的干预措施。
从PubMed、Cochrane Library、Web of Science、Embase、中国知网、万方数据库、维普数据库和中国生物医学文献数据库等 8 个数据库中检索 2021 年 1 月 1 日之前发表的比较女性 OAB 患者不同非药物干预措施的相关随机对照试验研究。筛选标题和摘要后,根据纳入标准提取参与者、干预措施和结局等详细数据。然后,使用 Cochrane 偏倚风险工具评估文献质量。使用 STATA 进行两两荟萃分析。通过 OpenBUGS、R 和 STATA 进行网络荟萃分析,比较和排名不同非药物干预措施在缓解症状、提高生活质量方面的效果。
本网络荟萃分析将提供治疗 OAB 以缓解症状和提高生活质量的最佳非药物干预措施的现有最佳证据。