Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, and the Program of Addiction Research, Clinical Care, Knowledge, and Advocacy (PARCKA), Division of Epidemiology, Department of Medicine, University of Utah School of Medicine, and Informatics, Decision-Enhancement, and Analytic Sciences Center (IDEAS 2.0), Salt Lake City VA Health Care System, Salt Lake City, Utah; and the Department of Obstetrics and Gynecology, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii.
Obstet Gynecol. 2018 Oct;132(4):926-928. doi: 10.1097/AOG.0000000000002871.
Kratom (Mitragyna speciosa) is an herbal preparation with opioid-like effects made from a tree native to Southeast Asia and the Pacific Islands. Increasingly, kratom is used for self-treatment of opioid use disorder and recently has been associated with a multistate outbreak of salmonellosis. Few data are available on the clinical outcomes of kratom use in pregnancy.
We present two cases of pregnant women presenting with kratom dependence. Both women presented with symptoms consistent with opioid withdrawal. Both women were initiated on opioid replacement, with successful treatment of symptoms.
Kratom is an emerging self-treatment for opioid use disorder in the obstetric population. Obstetric care providers should be aware of kratom and consider opioid replacement for pregnant women with kratom dependence.
Kratom（Mitragyna speciosa）是一种源自东南亚和太平洋岛屿的具有类阿片样作用的草药制剂。越来越多的人将其用于自我治疗阿片类药物使用障碍，最近还与多州沙门氏菌病疫情有关。关于妊娠期间使用 kratom 的临床结果的数据很少。
我们介绍了两例出现 kratom 依赖的孕妇病例。两名妇女均出现符合阿片类药物戒断症状。两名妇女均开始接受阿片类药物替代治疗，症状得到成功治疗。
Kratom 是产科人群中阿片类药物使用障碍的一种新兴自我治疗方法。产科护理提供者应该了解 kratom，并考虑对有 kratom 依赖的孕妇进行阿片类药物替代治疗。
