Abdullah Hafez Mohammad Ammar, Haq Iqra, Lamfers Randall
Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota, USA.
BMJ Case Rep. 2019 Jul 19;12(7):e229778. doi: 10.1136/bcr-2019-229778.
Kratom is a psychoactive herb that has stimulant properties at low doses and has opioid-like properties at higher doses. It has been used for centuries in southeast Asia as a stimulant but has gained increasing popularity as a substitute for opioids in western countries as it is easily available. As most cases of kratom use involve other drugs too, the Food and Drug Administration (FDA) has stopped short of restricting kratom due to difficulty in assessing the adverse effects of kratom alone. We present the case of a young healthy 35-year-old man who suffered a cardiac arrest due to kratom use with no other coingestants. He was subsequently intubated and found to have systolic dysfunction and small brain infarcts. Fortunately, he made a successful recovery and was discharged after a stay at thebehavioural health centre. Our case highlights the potential adverse effects of kratom and the need to regulate its use.
kratom是一种具有精神活性的草药，低剂量时具有兴奋特性，高剂量时具有类阿片特性。几个世纪以来，它在东南亚一直被用作兴奋剂，但在西方国家，由于其容易获取，作为阿片类药物的替代品越来越受欢迎。由于大多数使用kratom的案例也涉及其他药物，美国食品药品监督管理局（FDA）因难以单独评估kratom的不良反应而没有对其进行限制。我们报告了一例35岁年轻健康男性的病例，他因使用kratom而发生心脏骤停，没有其他合并摄入的药物。随后他被插管，发现有收缩功能障碍和小面积脑梗死。幸运的是，他成功康复，在行为健康中心住院一段时间后出院。我们的病例突出了kratom的潜在不良反应以及对其使用进行监管的必要性。
