a Retina and Uvea Services, Dr R P Centre for Ophthalmic Sciences , All India Institute of Medical Sciences , New Delhi , India.
b Department of Medicine , All India Institute of Medical Sciences , New Delhi , India.
Ocul Immunol Inflamm. 2019;27(3):383-388. doi: 10.1080/09273948.2018.1508729. Epub 2018 Sep 12.
: To evaluate patterns of retinal vasculitis with ultra-wide field imaging (UWF) and ascertain the risk factors for retinal neovascularization. : Consecutive patients of retinal vasculitis were included prospectively. Patients with retinal vasculitis secondary to uveitis were excluded. UWF was done for all the patients. Retinal involvement was classified into three zones and area of capillary non-perfusion was stratified into clock hours. : Two hundred patients were included, 85% ( = 170) were male. Mean age was 28.99 ± 10.56 years. Clinical examination revealed 65% cases ( = 130) to be bilateral, while UWF angiography detected 72.5% ( = 145) to have bilateral involvement. Retinal neovascularization was present in 47% ( = 188).Presence of posterior disease had very high odds ratio for development of retinal neovascularization as compared to cases restricted to retinal periphery (OR = 45.03, CI = 6.10-332.30, = < 0.001). : UWF imaging is useful in detecting retinal vasculitis, which is otherwise obscure to clinical examination and assessing risk factors for retinal neovascularization.
评估视网膜血管炎的超宽视野成像（UWF）模式，并确定视网膜新生血管形成的危险因素。
连续纳入视网膜血管炎患者进行前瞻性研究。排除因葡萄膜炎引起的视网膜血管炎患者。对所有患者进行 UWF 检查。将视网膜受累分为三个区，毛细血管无灌注区分为时钟小时。
共纳入 200 例患者，85%（170 例）为男性。平均年龄为 28.99±10.56 岁。临床检查显示 65%（130 例）为双侧，而 UWF 血管造影显示 72.5%（145 例）为双侧受累。47%（188 例）存在视网膜新生血管形成。与仅局限于视网膜周边的病例相比，后节疾病存在使视网膜新生血管形成的可能性增加 45.03 倍（OR=45.03，CI=6.10-332.30，P<0.001）。
UWF 成像有助于发现视网膜血管炎，这在临床检查中通常难以发现，并可评估视网膜新生血管形成的危险因素。
