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超广角眼底荧光血管造影在视网膜血管炎诊断和治疗中的应用

Ultra-widefield fundus fluorescein angiography in the diagnosis and management of retinal vasculitis.

作者信息

Jones N P, Sala-Puigdollers A, Stanga P E

机构信息

The Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

出版信息

Eye (Lond). 2017 Nov;31(11):1546-1549. doi: 10.1038/eye.2017.93. Epub 2017 Jun 2.

Abstract

PurposeTo quantify the additional information provided by ultra-widefield fluorescein angiography, compared with 7-field standard imaging, in patients with retinal vasculitis (RV).Patients and methodsRetrospective case series of 106 patients.ResultsRetinal vascular pathology was identified by UWF FFA, but not by standard ETDRS 7-field area, in 62 patients (58.5%) and in 79 eyes (43.4%). The pathology included active RV (47 eyes, 25.8% of eyes); retinal ischaemia, or infarction (53 eyes, 29.1%); and retinal neovascularization (7 eyes, 3.8%). A change to management was made in 36 patients (34%). Of these, 21 (20% of all patients undergoing angiography) were made after the identification of retinal vascular pathology, which was found only on UWF FFA, outside the ETDRS area.ConclusionUltra-widefield fluorescein angiography has clear advantages over standard multi-field imaging. It is currently the standard method of assessment for RV in this centre.

摘要

目的

量化超广角荧光素血管造影与七视野标准成像相比,为视网膜血管炎(RV)患者提供的额外信息。

患者与方法

对106例患者进行回顾性病例系列研究。

结果

62例患者(58.5%)和79只眼(43.4%)通过超广角荧光素血管造影(UWF FFA)发现视网膜血管病变,而标准的糖尿病视网膜病变早期治疗研究(ETDRS)七视野区域成像未发现。病变包括活动性视网膜血管炎(47只眼,占25.8%);视网膜缺血或梗死(53只眼,占29.1%);以及视网膜新生血管形成(7只眼,占3.8%)。36例患者(34%)的治疗方案发生了改变。其中,21例(占所有接受血管造影患者的20%)是在发现视网膜血管病变后做出的改变,这些病变仅在ETDRS区域外的超广角荧光素血管造影中发现。

结论

超广角荧光素血管造影比标准的多视野成像具有明显优势。它目前是本中心评估视网膜血管炎的标准方法。

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本文引用的文献

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Ultra-wide-field fluorescein angiography of the ocular fundus.眼底超广角荧光血管造影
Am J Ophthalmol. 2005 Sep;140(3):525-7. doi: 10.1016/j.ajo.2005.02.055.

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