Department of Computer Photonics and Videomatics, ITMO University, 49 Kronverksky Pr., 197101, St. Petersburg, Russia.
Department of Circulation Physiology, Almazov National Medical Research Centre, 2 Akkuratova St., 197341, St. Petersburg, Russia.
Sci Rep. 2018 Sep 12;8(1):13663. doi: 10.1038/s41598-018-32036-7.
The velocity of the pulse wave (PWV) propagating through the vascular tree is an essential parameter for diagnostic the state of the cardiovascular system especially when it is measured in the pool of carotid arteries. In this research, we showed for the first time that the time of the blood-pressure-wave propagation from the heart to the face is a function of the body position. Significant asymmetry and asynchronicity of blood pulsations in the facial area were found in a recumbent position. Parameters of blood pulsations were measured by an advanced camera-based photoplethysmography system in 73 apparently healthy subjects. Most likely, observed changes of the blood-pulsation parameters are caused by variations of the arterial blood pressure due to hydrostatic pressure changes, and secondary reaction of blood vessels in response to these variations. Demonstrated feasibility of PWV measurements in the pool of carotid arteries provides considerable advantages over other technologies. Moreover, possibilities of the method to estimate physiological regulation of the peripheral blood flow (particularly, as a response to the gravitational changes) have been demonstrated. The proposed concept allows development of non-invasive medical equipment capable of solving a wide range of scientific and practical problems related to vascular physiology.
脉搏波在血管树中传播的速度是诊断心血管系统状态的一个重要参数，特别是当它在颈动脉池中测量时。在这项研究中，我们首次表明，从心脏到面部的血压波传播时间是身体姿势的函数。在卧位时，面部区域的血液搏动存在明显的不对称性和不同步性。通过先进的基于摄像机的光体积描记系统，在 73 名明显健康的受试者中测量了血液搏动的参数。很可能，观察到的血液搏动参数的变化是由于动脉血压由于静水压力变化而发生变化，以及血管对这些变化的继发性反应引起的。在颈动脉池中测量脉搏波速度的可行性提供了比其他技术更大的优势。此外，该方法估计外周血流量的生理调节（特别是作为对重力变化的反应）的可能性已经得到证明。所提出的概念允许开发能够解决与血管生理学相关的广泛科学和实际问题的非侵入性医疗设备。
