Wang Xu, Zhou Hong-lei, Rong Rong
Zhong Yao Cai. 2016 Sep;39(9):2030-2.
To study the chemical constituents of the methylene chloride extract of Lonicerae Japonicae Flos.
The compounds were isolated and purified by silica gel column chromatography,Sephadex LH-20 gel column chromatography and recrystallization. The structures were elucidated by the physical and chemical properties,MS,1H-NMR and13C-NMR spectroscopy.
Nine compounds were isolated and their structures were identified as β-sitosterol( 1),benzoic acid( 2),5-hydroxy-7,3’,4’-trimethoxyflavone( 3),tetrapedic acid B( 4),tricin( 5),hydnocarpin D( 6),6,7,10-trihydroxy-8-octadecenoic acid( 7),5’-methoxyhydnocarpin-D( 8) and daucosterol( 9).
Compound 2,4,7,8 are isolated from this plant,compounds 2,7,8 are isolated from Caprifoliaceae family for the first time.
研究金银花二氯甲烷提取物的化学成分。
采用硅胶柱色谱、Sephadex LH - 20凝胶柱色谱及重结晶法对化合物进行分离纯化。通过理化性质、质谱、1H - NMR和13C - NMR光谱对结构进行鉴定。
分离得到9个化合物，其结构分别鉴定为β-谷甾醇（1）、苯甲酸（2）、5 - 羟基 - 7,3',4' - 三甲氧基黄酮（3）、四季青酸B（4）、小麦黄素（5）、氢化卡维丁D（6）、6,7,10 - 三羟基 - 8 - 十八碳烯酸（7）、5'-甲氧基氢化卡维丁 - D（8）和胡萝卜苷（9）。
化合物2、4、7、8为首次从该植物中分离得到，化合物2、7、8为首次从忍冬科植物中分离得到。
