Kreiswirth B N, Kravitz G R, Schlievert P M, Novick R P
Ann Intern Med. 1986 Nov;105(5):704-7. doi: 10.7326/0003-4819-105-5-704.
A strain of Staphylococcus aureus producing toxic shock syndrome toxin-1 was repeatedly isolated from the nares of a neurosurgeon. This strain was identical to strains cultured from two of his patients who developed toxic shock syndrome after laminectomy. The relatedness of the isolates was shown by Southern blot hybridization analyses using chromosomal transposons as probes. This approach should be considered, in addition to standard bacteriologic techniques, as an effective method to analyze the relatedness of nosocomial isolates.
从一位神经外科医生的鼻腔中反复分离出一株产中毒性休克综合征毒素-1的金黄色葡萄球菌。该菌株与从他的两名患者身上培养出的菌株相同，这两名患者在椎板切除术后发生了中毒性休克综合征。使用染色体转座子作为探针，通过Southern印迹杂交分析显示了分离株之间的相关性。除了标准的细菌学技术外，这种方法应被视为分析医院感染分离株相关性的一种有效方法。
