Department of Urology, Seoul National University Boramae Medical Center, Seoul, Korea.
Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea.
PLoS One. 2018 Sep 13;13(9):e0203825. doi: 10.1371/journal.pone.0203825. eCollection 2018.
This study aimed to determine serial changes in self-assessed goal achievement (SAGA) and treatment satisfaction after HoLEP, to identify correlations between the two, and to compare them with results assessed by traditional outcome measures. For a total of 170 patients, outcomes were evaluated serially at postoperative 1-, 3-, 6-, and 12-months using IPSS, OABSS, SAGA questionnaires and uroflowmetry. The SAGA questionnaire consisted of five questions including one open-ended question (self-assessed goals and degree of SAGA) and another question regarding treatment satisfaction. The number of self-assessed treatment goals was two or more in 74.1% of the patients. Most common treatment goal was relief from straining/hesitancy, followed by increased daytime frequency, nocturia and feeling of incomplete emptying. Degree of achievement for the first or second goal and treatment satisfaction tended to increase with time throughout the follow-up period. Patients with the greatest treatment satisfaction scores showed greater improvement by traditional outcome parameters including quality of life (QOL) index, total OABSS, maximum flow rate (Qmax), post-void residual urine volume (PVR) and bladder voiding efficiency (BVE) compared to those without treatment satisfaction. After adjusting for other influential variables, the improvements in subjective outcome parameters including total IPSS, QOL index and total OABSS were significantly associated with treatment satisfaction, but improvements in objective outcome parameters including Qmax, PVR and BVE were not. In addition, the degree of SAGA for the first goal or second goal was more predictive in determining treatment satisfaction than the traditional outcome measures. In conclusion, treatment goals of patients with lower urinary tract symptoms (LUTS)/BPH vary from individual to individual. The degree of SAGA and treatment satisfaction for HoLEP tends to increase with time throughout the follow-up period. Compared to the traditional outcome measures, the degree of goal achievement can be more predictive when assessing patient-centered outcomes such as treatment satisfaction.
本研究旨在确定 HoLEP 术后自我评估目标达成(SAGA)和治疗满意度的连续变化,确定两者之间的相关性,并将其与传统的疗效评估方法进行比较。共 170 例患者,术后 1、3、6、12 个月分别采用 IPSS、OABSS、SAGA 问卷和尿流率测定对患者进行随访,评估 SAGA 问卷包括五个问题,其中一个是开放式问题(自我评估目标和 SAGA 程度),另一个是治疗满意度问题。在患者中,有 74.1%的患者自我评估的治疗目标为 2 个或更多。最常见的治疗目标是缓解排尿困难/犹豫,其次是白天尿频、夜尿和排空感不完全。在整个随访期间,第一或第二目标的达成程度和治疗满意度随着时间的推移而增加。治疗满意度评分最高的患者,其传统疗效参数(包括生活质量[QOL]指数、总 OABSS、最大尿流率[Qmax]、残余尿量[PVR]和膀胱排空效率[BVE])改善更为显著,而治疗满意度较差的患者则不然。在调整其他影响因素后,主观疗效参数(包括总 IPSS、QOL 指数和总 OABSS)的改善与治疗满意度显著相关,而客观疗效参数(包括 Qmax、PVR 和 BVE)的改善则无明显相关性。此外,SAGA 第一目标或第二目标的达成程度比传统的疗效评估方法更能预测治疗满意度。总之,下尿路症状(LUTS)/前列腺增生(BPH)患者的治疗目标因人而异。随着随访时间的延长,HoLEP 术后 SAGA 程度和治疗满意度呈上升趋势。与传统的疗效评估方法相比,在评估以患者为中心的治疗满意度等结局时,目标达成程度的预测价值更高。