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比较传统的疗效评估指标和患者自报的前列腺良性增生症手术治疗目标达成情况。

Comparison of traditional outcome measures and self-assessed goal achievement in patients treated surgically for benign prostatic hyperplasia.

机构信息

Department of Urology, School of Medicine, University of St. Gallen, St. Gallen, Switzerland.

Department of Urology, University of California, Davis, Sacramento, CA, USA.

出版信息

World J Urol. 2023 Apr;41(4):1125-1131. doi: 10.1007/s00345-023-04317-y. Epub 2023 Feb 16.

Abstract

PURPOSE

To determine self-assessed goal achievement (SAGA) outcomes in men treated surgically for lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO) and compare them to the traditional outcome measures.

METHODS

Single-center analysis of prospective database of men undergoing surgical treatment of LUTS/BPO at a single institution between July 2019 and March 2021. We assessed individual goals, traditional questionnaires, and functional outcomes prior to treatment, and at first follow-up after 6-12 weeks. We compared SAGA outcomes 'overall goal achievement' and 'satisfaction with treatment' to subjective and objective outcomes using Spearman's rank correlations (rho).

RESULTS

A total of sixty-eight patients completed the individual goal formulation prior to surgery. Preoperative goals varied between different treatments and individuals. IPSS correlated with 'overall goal achievement' (rho = - 0.78, p < 0.001) and 'satisfaction with treatment' (rho = - 0.59, p < 0.001). Similarly, the IPSS-QoL was correlated with overall goal achievement (rho = - 0.79, p < 0.001) and satisfaction with treatment (rho = - 0.65, p < 0.001). No correlation was seen between SAGA outcomes and functional outcomes Q and PVR.

CONCLUSIONS

SAGA represents a uniquely patient-specific outcome measure. Our study is, to our knowledge, the first to assess patient-specific goals prior to surgery and examine SAGA outcomes following treatment in men suffering from LUTS/BPO. The correlation of SAGA outcomes with IPSS and IPSS-QoL highlight the importance of this well-established questionnaire. Functional outcomes do not necessarily reflect patient's goals and may rather be considered physician-directed outcomes.

摘要

目的

评估接受手术治疗的良性前列腺梗阻(BPO)导致下尿路症状(LUTS)男性的自我评估目标达成(SAGA)结果,并与传统的结局指标进行比较。

方法

对 2019 年 7 月至 2021 年 3 月期间在单一机构接受 LUTS/BPO 手术治疗的男性进行前瞻性数据库的单中心分析。我们在治疗前和治疗后 6-12 周的首次随访时评估了个体目标、传统问卷和功能结局。我们使用 Spearman 秩相关(rho)比较 SAGA 结局的“总体目标达成”和“对治疗的满意度”与主观和客观结局。

结果

共有 68 例患者在手术前完成了个体化目标制定。术前目标因不同治疗和个体而异。IPSS 与“总体目标达成”(rho=-0.78,p<0.001)和“对治疗的满意度”(rho=-0.59,p<0.001)相关。同样,IPSS-QoL 与总体目标达成(rho=-0.79,p<0.001)和对治疗的满意度(rho=-0.65,p<0.001)相关。SAGA 结局与 Q 和 PVR 等功能结局之间无相关性。

结论

SAGA 代表了一种独特的基于患者的结局测量方法。据我们所知,我们的研究首次在手术前评估了患者特定的目标,并在 LUTS/BPO 男性接受治疗后检查了 SAGA 结局。SAGA 结局与 IPSS 和 IPSS-QoL 的相关性突出了这个成熟问卷的重要性。功能结局不一定反映患者的目标,而可能被视为医生指导的结局。

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