在人肝细胞长期单层培养物中α-1-抗胰蛋白酶的体外合成
In vitro synthesis of alpha-1-antitrypsin in long term monolayer human liver cell cultures.
作者信息
Gautier M, Martin J P, Polini G
出版信息
Biomedicine. 1977 Apr;27(3):116-9.
PMID:302126
Abstract
Explants for long term monolayer liver cell cultures were taken from individuals having PiM or PiZ phenotypes. Radioactive labelling, using I125 and an original method, permitted the quantitative measurement of AAT in vitro and more important, allowed Pi phenotype determination.
摘要
用于长期单层肝细胞培养的外植体取自具有PiM或PiZ表型的个体。使用碘125和一种原创方法进行放射性标记，能够在体外对α1抗胰蛋白酶（AAT）进行定量测量，更重要的是，可以确定Pi表型。
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