Herrero A, Thompson K D, Ashby A, Rodger H D, Dagleish M P
Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Scotland, United Kingdom.
Fish Vet Group Ltd., 22 Carsegate Road, Inverness, Scotland, UK.
J Comp Pathol. 2018 Aug;163:23-28. doi: 10.1016/j.jcpa.2018.07.004. Epub 2018 Aug 16.
Gill disorders have become a significant problem during the marine phase of farming Atlantic salmon (Salmo salar L.). The term complex gill disease (CGD) includes a wide range of clinical gill disease presentations generally occurring from the end of summer to early winter on marine Atlantic salmon farms. The gross and histological lesions observed are the resultant culmination of exposure to a mixture of environmental insults, pathogenic organisms and farm management practices. None of the three principal agents purportedly associated with CGD (Desmozoon lepeophtherii, salmon gill poxvirus or Candidatus Branchiomonas cysticola) have been cultured successfully in-vitro, so individual in-vivo challenge studies to identify their pathogenesis have not been possible. Studies of cohabitation of single pathogen-infected fish with naïve fish, and epidemiological investigations are required urgently to elucidate the roles of these pathogens and other factors in CGD.
鳃病已成为大西洋鲑（Salmo salar L.）养殖海水阶段的一个重大问题。复合鳃病（CGD）这一术语涵盖了广泛的临床鳃病表现，通常发生在海水养殖的大西洋鲑养殖场，时间从夏末到初冬。观察到的大体和组织学病变是暴露于环境损害、致病生物和养殖管理实践等多种因素共同作用的结果。据称与CGD相关的三种主要病原体（鲑居尾孢虫、鲑鳃痘病毒或新鞘氨醇单胞菌）均未在体外成功培养，因此无法通过个体体内攻毒研究来确定它们的致病机制。迫切需要开展单一病原体感染鱼与未感染鱼的共居研究以及流行病学调查，以阐明这些病原体和其他因素在CGD中的作用。
