用于治疗肺部真菌病的药物药理学。
The pharmacology of agents used in the treatment of pulmonary mycoses.
作者信息
Borgers M, Vanden Bossche H, Cauwenbergh G
出版信息
Clin Chest Med. 1986 Sep;7(3):439-52.
PMID:3021382
Abstract
The different antifungals currently used in pulmonary mycoses consist of polyene antibiotics, the antimetabolite 5-fluorocytosine, and azole derivatives. The pharmacologic profiles, mechanisms of action, pharmacokinetics, clinical indications for use, dosage recommendations, side effects, and drug interactions for these agents are presented.
摘要
目前用于肺部真菌病的不同抗真菌药物包括多烯类抗生素、抗代谢物5-氟胞嘧啶和唑类衍生物。本文介绍了这些药物的药理学概况、作用机制、药代动力学、临床应用指征、剂量推荐、副作用及药物相互作用。
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