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切尔西重症监护物理评估(CPAx)工具对重症监护病房手术和创伤患者临床结局的影响:一项实验研究。

Impact of the Chelsea critical care physical assessment (CPAx) tool on clinical outcomes of surgical and trauma patients in an intensive care unit: An experimental study.

作者信息

Whelan Megan, van Aswegen Heleen, Corner Evelyn

机构信息

Department of Physiotherapy, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, South Africa.

Department of Clinical Sciences, Brunel University London, United Kingdom.

出版信息

S Afr J Physiother. 2018 Aug 23;74(1):450. doi: 10.4102/sajp.v74i1.450. eCollection 2018.

Abstract

BACKGROUND

Critically ill patients following traumatic injury or major surgery are at risk of loss of skeletal muscle mass, which leads to decreased physical function. Early rehabilitation in an intensive care unit (ICU) is thought to preserve or restore physical functioning. The Chelsea critical care physical assessment (CPAx) is a measurement tool used to assess physical function in the ICU.

OBJECTIVES

To determine whether the use of the CPAx tool as part of physiotherapy patient assessment, in two adult trauma and surgical ICU settings where early patient mobilisation forms part of standard physiotherapy practice, had an impact on ICU and hospital length of stay (LOS) through delivery of problem-oriented treatment plans.

METHOD

A single-centred pre-post quasi-experimental study was conducted. The population was a consecutive sample of surgical and trauma ICU patients. Participants' functional ability was assessed with the CPAx tool on alternative days during their ICU stay, and rehabilitation goals were modified according to their CPAx score. Intensive care unit and hospital LOS data were collected and compared to data of a matched historical control group. Descriptive and inferential statistics were used.

RESULTS

A total of 26 ICU patients were included in the intervention group ( = 26). They received CPAx-guided therapy, and outcomes were matched with ICU patients in the historical control group ( = 26). The median sequential organ failure assessment (SOFA) score was significantly higher in the control group ( = 0.005) (3.5 [IQR 2-6.3]) versus (2 [IQR 1.8-2.5]) for the intervention group. The median admission CPAx score for the intervention group was 33.5 (IQR 16.1-44), and the median ICU discharge score was 38 (IQR 28.5-43.8). No significant differences were found in ICU days (control 2.7 [IQR 1.1-5.2]; intervention 3.7 [IQR 2.3-5.4]; = 0.27) or hospital LOS (control 13.5 [IQR 9.3-18.3]; intervention 11.4 [IQR 8.4-20.3], = 0.42). Chelsea critical care physical assessment scores on ICU admission had a moderate negative correlation with hospital LOS ( = -0.58, = 0.00, = 23). Chelsea critical care physical assessment scores at ICU discharge had strong positive correlation with discharge SOFA scores ( = 0.7; = 0.025; = 10).

CONCLUSION

Problem-oriented patient rehabilitation informed by the CPAx tool resulted in improvement of physical function but did not reduce ICU or hospital LOS.

CLINICAL IMPLICATIONS

A higher level of physical function at ICU admission, measured with CPAx, was associated with shorter hospital LOS.

摘要

背景

创伤性损伤或大手术后的重症患者存在骨骼肌质量丢失的风险,这会导致身体功能下降。重症监护病房(ICU)的早期康复被认为可以维持或恢复身体功能。切尔西重症监护身体评估(CPAx)是一种用于评估ICU患者身体功能的测量工具。

目的

在两个成年创伤和外科ICU环境中,早期患者活动是标准物理治疗实践的一部分,确定将CPAx工具用作物理治疗患者评估的一部分,通过提供以问题为导向的治疗计划,是否会对ICU和医院住院时间(LOS)产生影响。

方法

进行了一项单中心前后准实验研究。研究对象是外科和创伤ICU患者的连续样本。在ICU住院期间,每隔一天使用CPAx工具评估参与者的功能能力,并根据其CPAx评分修改康复目标。收集ICU和医院LOS数据,并与匹配的历史对照组数据进行比较。使用描述性和推断性统计方法。

结果

干预组共纳入26例ICU患者(n = 26)。他们接受了CPAx指导的治疗,结果与历史对照组的ICU患者(n = 26)相匹配。对照组的序贯器官衰竭评估(SOFA)评分中位数显著更高(P = 0.005)(3.5[四分位间距2 - 6.3]),而干预组为(2[四分位间距1.8 - 2.5])。干预组的入院CPAx评分中位数为33.5(四分位间距16.1 - 44),ICU出院评分中位数为38(四分位间距28.5 - 43.8)。在ICU住院天数(对照组2.7[四分位间距1.1 - 5.2];干预组3.7[四分位间距2.3 - 5.4];P = 0.27)或医院LOS方面未发现显著差异(对照组13.5[四分位间距9.3 - 18.3];干预组11.4[四分位间距8.4 - 20.3],P = 0.42)。ICU入院时的切尔西重症监护身体评估评分与医院LOS呈中度负相关(r = -0.58,P = 0.00,n = 23)。ICU出院时的切尔西重症监护身体评估评分与出院SOFA评分呈强正相关(r = 0.7;P = 0.025;n = 10)。

结论

以CPAx工具为依据的以问题为导向的患者康复可改善身体功能,但并未缩短ICU或医院LOS。

临床意义

用CPAx测量的ICU入院时较高水平的身体功能与较短的医院LOS相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ca2/6131696/500548be4777/SAJP-74-450-g001.jpg

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