Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
BMC Genomics. 2018 Sep 14;19(1):676. doi: 10.1186/s12864-018-5046-6.
Pseudocohnilembus persalinus, a unicellular ciliated protozoan, is one of commonest facultative pathogens. We sequenced the macronuclear genome of P. persalinus in 2015, which provided new insights into its pathogenicity.
Here, we present the P. persalinus genome database (PPGD) ( http://ciliates.ihb.ac.cn/database/home/#pp ), the first genome database for the scuticociliatosis pathogens. PPGD integrates P. persalinus macronuclear genomic and transcriptomic data, including genome sequence, transcript, gene expression data, and gene annotation, as well as relevant information on its biology, morphology and taxonomy. The database also provides functions for visualizing, analyzing, and downloading the data.
PPGD is a useful resource for studying scuticociliates or scuticociliatosis. We will continue to update the PPGD by integrating more data and aim to integrate the PPGD with other ciliate databases to build a comprehensive ciliate genome database.
Pseudocohnilembus persalinus 是一种单细胞纤毛原生动物，是最常见的兼性病原体之一。我们于 2015 年对 P. persalinus 的大核基因组进行了测序，这为其致病性提供了新的见解。
在这里，我们展示了 P. persalinus 基因组数据库（PPGD）（http://ciliates.ihb.ac.cn/database/home/#pp），这是首个针对旋毛体病病原体的基因组数据库。PPGD 整合了 P. persalinus 大核基因组和转录组数据，包括基因组序列、转录本、基因表达数据和基因注释，以及有关其生物学、形态学和分类学的相关信息。该数据库还提供了可视化、分析和下载数据的功能。
PPGD 是研究旋毛虫或旋毛虫病的有用资源。我们将继续通过整合更多的数据来更新 PPGD，并旨在将 PPGD 与其他纤毛动物数据库集成，以构建一个全面的纤毛动物基因组数据库。
