Tanabe Kazuaki, Sakamoto Takahiro
Division of Cardiology, Faculty of Medicine, Shimane University, 89-1 Enya-cho, Izumo, 693-8501, Japan.
J Echocardiogr. 2019 Mar;17(1):5-9. doi: 10.1007/s12574-018-0396-2. Epub 2018 Sep 14.
Substantial or complete myocardial recovery occurs in many patients with heart failure (HF). HF patients with myocardial recovery or recovered left ventricular (LV) ejection fraction (EF; HFrecEF) are a distinct population of HF patients with different underlying etiologies, comorbidities, response to therapies, and outcomes compared with HF patients with persistent reduced or preserved EF. Improvement in LVEF has been systematically linked to improved quality of life, and lower rehospitalization rates and mortality. However, the mortality and morbidity in HFrecEF patients remain higher than those in the normal population. Currently, data to guide the management of HFrecEF patients are lacking. This review discusses specific characteristics, pathophysiology, and clinical implications for HFrecEF.
许多心力衰竭（HF）患者会出现显著或完全的心肌恢复。与左心室（LV）射血分数（EF）持续降低或保留的HF患者相比，心肌恢复或左心室射血分数恢复（HFrecEF）的HF患者是一个不同的HF患者群体，其潜在病因、合并症、对治疗的反应和预后各不相同。左心室射血分数的改善与生活质量的提高、再住院率和死亡率的降低有着系统性的关联。然而，HFrecEF患者的死亡率和发病率仍高于正常人群。目前，缺乏指导HFrecEF患者管理的数据。本综述讨论了HFrecEF的具体特征、病理生理学和临床意义。
