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利用环鸟苷 3',5'-单磷酸（cGMP）从 B 淋巴细胞的肌浆网动员细胞内钙。

Mobilization of intracellular calcium from the sarcoplasmic reticulum of B-lymphocytes using cyclic guanosine 3'5'-monophosphate (cGMP).

作者信息

Dontsov V I

出版信息

J Hyg Epidemiol Microbiol Immunol. 1986;30(3):295-9.

PMID:3021844
Abstract

Cyclic guanosine-3'5' monophosphate (cGMP) can mobilize intracellular calcium from the microsomal fraction of B-lymphocytes of the mouse spleen as a result of activation of cGMP-dependent microsomal proteinkinases. The existence of such a mechanism makes B-lymphocytes independent of extracellular calcium in response to agents whose effect on B-lymphocytes is mediated by calcium mechanisms.

摘要

环磷酸鸟苷（cGMP）可通过激活依赖cGMP的微粒体蛋白激酶，从小鼠脾脏B淋巴细胞的微粒体部分动员细胞内钙。这种机制的存在使B淋巴细胞在对其对B淋巴细胞的作用由钙机制介导的试剂作出反应时，不依赖细胞外钙。

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