Smith E B
Z Gesamte Inn Med. 1978 Sep 1;33(17):605-6.
LDL, fibrinogen and other plasma macromolecules are retained in intima in substantial amounts. In areas where lipid is accumulating a large part of LDL is immobilized possibily by binding to fibrin. Lipid may be deposited from LDL as a result of degradation by a cathepsin in intima.
低密度脂蛋白(LDL)、纤维蛋白原和其他血浆大分子大量滞留在内膜中。在脂质积聚的区域,很大一部分低密度脂蛋白可能通过与纤维蛋白结合而固定。由于内膜中的组织蛋白酶降解,脂质可能从低密度脂蛋白中沉积出来。