National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation, Moscow, Russia.
Peoples' Friendship University of Russia, Moscow, Russia.
Stem Cell Res Ther. 2018 Sep 15;9(1):236. doi: 10.1186/s13287-018-0992-0.
In this review we present current evidence on the possibility of umbilical cord tissue cryopreservation for subsequent clinical use. Protocols for obtaining umbilical cord-derived vessels, Wharton's jelly-based grafts, multipotent stromal cells, and other biomedical products from cryopreserved umbilical cords are highlighted, and their prospective clinical applications are discussed. Examination of recent literature indicates we should expect high demand for cryopreservation of umbilical cord tissues in the near future.
在这篇综述中,我们介绍了脐带组织冷冻保存以备后续临床应用的可能性的现有证据。强调了从冷冻保存的脐带中获取脐带血管、华通氏胶基质移植物、多能基质细胞和其他生物医学产品的方案,并讨论了它们的预期临床应用。对近期文献的研究表明,我们应该预计在不久的将来对脐带组织的冷冻保存有很高的需求。