Pan W, Liu Z, Zhao Z H, Li J, Zeng C C, Zhu Z Z, Wang B, Qian B P, Yu Y, Qiu Y
Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing 210008, China.
Zhonghua Yi Xue Za Zhi. 2018 Sep 4;98(33):2650-2655. doi: 10.3760/cma.j.issn.0376-2491.2018.33.008.
To analyze the long-term results and the influence factors of spontaneous correction of unfused thoracic curves in anterior and posterior selective fusions in Lenke type 5C adolescent idiopathic scoliosis (AIS). From January 2005 to December 2011, 89 Lenke type 5C AIS patients with a minimum of 5-year follow-up who underwent thoracolumbar/lumbar (TL/L) selective fusion in Spine Surgery of Nanjing Drum Tower Hospital were reviewed.Forty-six patients underwent anterior fusion (anterior group), while 46 underwent posterior fusion (posterior group). The following radiological parameters were measured and analyzed at pre-operation, post-operation, and latest follow-up: curve magnitude of primary thoracolumbar/lumbar and secondary thoracic curve, trunk shift, thoracic apical vertebral translation, upper instrumented vertebra tilt, thoracic kyphosis, proximal junctional angle, sagittal vertical axis. Independent sample test was used to compare the above parameters between the two groups. Compared with those in posterior group, anterior group were found with less fusion levels (5.4±0.6 vs 5.9±0.8, =3.318, =0.001) and longer operation time[(276±28)min vs (186±36)min, =13.101, <0.001]. Immediately after surgery, the spinal deformity was significantly corrected in the two groups. The mean spontaneous correction rates of the minor curve were 50%±21% and 56%±20% in anterior and posterior groups, respectively (=1.489, =0.140). After a mean follow-up of (6.8±1.7) years in anterior group and (6.3±1.3) years in posterior group, the spontaneous correction rate of minor curve was maintained at 46%±22% and 49%±19%, respectively (=0.703, =0.484), with no significant correction loss. Other radiographic parameters were also stably maintained. According to the correlation analysis, the spontaneous correction rate was significantly correlated with upper instrumented vertebra (UIV) tilt in both groups (anterior: =-0.526, posterior: =-0.399, both <0.05). Both anterior and posterior selective fusion can achieve satisfactory spontaneous correction of unfused thoracic curves in Lenke type 5C AIS, with no significant difference between the two surgical approaches. UIV tilt is a key influence factor of spontaneous correction of thoracic curves.
分析Lenke 5C型青少年特发性脊柱侧凸(AIS)前路和后路选择性融合术中未融合胸弯自发矫正的长期结果及影响因素。回顾2005年1月至2011年12月在南京鼓楼医院脊柱外科接受胸腰段/腰段(TL/L)选择性融合且至少随访5年的89例Lenke 5C型AIS患者。46例患者接受前路融合(前路组),46例接受后路融合(后路组)。在术前、术后及末次随访时测量并分析以下影像学参数:主胸腰段/腰段及次胸弯的曲线大小、躯干偏移、胸顶椎平移、上固定椎倾斜度、胸椎后凸、近端交界角、矢状垂直轴。采用独立样本t检验比较两组上述参数。结果显示,与后路组相比,前路组融合节段更少(5.4±0.6比5.9±0.8,t =3.318,P =0.001),手术时间更长[(276±28)分钟比(186±36)分钟,t =13.101,P <0.001]。术后即刻,两组脊柱畸形均得到显著矫正。前路组和后路组次要曲线的平均自发矫正率分别为50%±21%和56%±20%(t =1.489,P =0.140)。前路组平均随访(6.8±1.7)年,后路组平均随访(6.3±1.3)年,次要曲线的自发矫正率分别维持在46%±22%和49%±19%(t =0.703,P =0.484),无明显矫正丢失。其他影像学参数也保持稳定。相关性分析显示,两组自发矫正率均与上固定椎(UIV)倾斜度显著相关(前路:r =-0.526,后路:r =-0.399,均P <0.05)。前路和后路选择性融合均可使Lenke 5C型AIS未融合胸弯获得满意的自发矫正,两种手术方式之间无显著差异。UIV倾斜度是胸弯自发矫正的关键影响因素。