Chen M X, Liu Y M, Wei W B
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing 100730, China.
Zhonghua Yan Ke Za Zhi. 2018 Sep 11;54(9):707-711. doi: 10.3760/cma.j.issn.0412-4081.2018.09.017.
Radiation treatment, including episcleral plaque radiotherapy, stereotactic radiosurgery, proton beam therapy and so on, is the primary eye-conserving choice for uveal melanoma. But the complications resulted from radiotherapy's nonselective kill to tumor cells can be visual-threatening and eventually result in the enucleation of eyeball. This review summarizes current radiation strategies for uveal melanoma and how these complications occur, develop and present, in the hope that it could provide insights for the radiation interventions and diagnosis of radiative complications. .
放射治疗,包括巩膜外斑块放射治疗、立体定向放射外科、质子束治疗等,是葡萄膜黑色素瘤主要的保眼治疗选择。但放射治疗对肿瘤细胞的非选择性杀伤所导致的并发症可能会威胁视力,最终导致眼球摘除。本综述总结了目前葡萄膜黑色素瘤的放射治疗策略以及这些并发症如何发生、发展和表现,希望能为放射治疗干预和放射性并发症的诊断提供见解。