早产儿视网膜病变中眼内抗血管内皮生长因子“紧缩”效应
Fellow Eye Anti-VEGF 'Crunch' Effect in Retinopathy of Prematurity.
作者信息
Wood Edward H, Rao Prethy, Moysidis Stavros N, Dedania Vaidehi S, Elman Michael J, Drenser Kimberly A, Capone Antonio, Trese Michael T
出版信息
Ophthalmic Surg Lasers Imaging Retina. 2018 Sep 1;49(9):e102-e104. doi: 10.3928/23258160-20180907-16.
BACKGROUND AND OBJECTIVE
Anti-vascular endothelial growth factor (VEGF) therapy is increasing in popularity for treatment of retinopathy of prematurity (ROP). Despite many technical benefits, issues remain prompting further investigation.
PATIENTS AND METHODS
Retrospective case report and literature review.
RESULTS
A 42-week-old postmenstrual age female with gestational age of 28 weeks and birth weight of 990 g presented with prominent progression of peripapillary purely tractional atypical stage 4A ROP in both eyes following intravitreal bevacizumab therapy in the right eye only.
CONCLUSION
The authors present the first reported case, to their knowledge, of a "crunch" phenomenon tractional retinal detachment from fellow eye administration of bevacizumab. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e102-e104.].
背景与目的
抗血管内皮生长因子（VEGF）疗法在早产儿视网膜病变（ROP）的治疗中越来越受欢迎。尽管有许多技术优势，但问题仍然存在，促使进一步研究。
患者与方法
回顾性病例报告及文献综述。
结果
一名孕42周龄的女性，孕龄28周，出生体重990克，仅右眼接受玻璃体内贝伐单抗治疗后，双眼出现视乳头周围单纯牵拉性非典型4A期ROP显著进展。
结论
据作者所知，本文首次报道了因对侧眼给予贝伐单抗而出现“嘎吱”现象牵拉性视网膜脱离的病例。[《眼科手术、激光与视网膜成像》。2018年；49:e102 - e104。]
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