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[小儿复杂先天性肠闭锁的治疗经验]

[Experience in treatment of complex congenital intestinal atresia in children].

作者信息

Zhang Shisong, Wu Yurui, Liu Hongzhen, Zhai Yunpeng, Liu Wei

机构信息

Department of Thoracic and Oncological Surgery, Qilu Children's Hospital of Shandong University, Jinan 250022, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2018 May 25;47(3):255-260. doi: 10.3785/j.issn.1008-9292.2018.06.06.

Abstract

OBJECTIVE

To summarize experience in the treatment of complex congenital intestinal atresia in children, so as to investigate the key points and effect of the operation.

METHODS

Medical notes of 49 children with complex intestinal atresia treated between January 2012 and January 2018 were reviewed. The information of age, sex, age at operation, full-term or premature, birth weight, clinical manifestation, auxiliary examination, preliminary diagnosis, treatment process, discharge diagnosis, pathological results and prognosis of patients were analyzed.

RESULTS

All patients underwent surgical treatment, including 42 cases with laparotomy (85.7%) and 7 with laparoscopic surgery (14.3%); 1 case undergoing laparoscopic surgery was converted to laparotomy due to meconium peritonitis. The mean operation time was (147±43) min (70-270 min); the mean fasting time after surgery was (8±3) d (4-16 d); the mean parenteral nutrition time was (12±6) d (3-30 d). Eleven cases were discharged against medical after operation and lost to follow-up. Among rest 38 children, 1 child (2.6%) received intestinal resection and ostomy five days after operation due to gastrointestinal perforation; 1 child (2.6%) received conservative treatment one month later due to adhered intestinal obstruction and left hospital with cure; 1 child (2.6%) received enterodialysis and ileostomy eight days after operation due to anastomotic leak, and received the operation for the closure of fistula after three months; 4 children had complications including fluid and electrolyte disorders, anemia, hypoproteinemia and so on, and recovered after conservative treatments. Postoperative follow-up showed that 1 child with duodenal atresia had lower body weight at 6 month after operation, but the body weight returned to normal when the child was one year old; 1 child with preterm labor of 32 weeks was treated with enteral nutrition, and gradually restored the normal diet after 6 months. Growth retardation was not observed in other children.

CONCLUSIONS

With active treatment and reservation of normal bowel tube as much as possible during the operation, the prognosis of children with complex intestinal atresia is usually favorable.

摘要

目的

总结小儿复杂先天性肠闭锁的治疗经验,探讨手术要点及效果。

方法

回顾性分析2012年1月至2018年1月收治的49例小儿复杂肠闭锁的病历资料。对患儿的年龄、性别、手术年龄、足月或早产、出生体重、临床表现、辅助检查、初步诊断、治疗过程、出院诊断、病理结果及预后等资料进行分析。

结果

所有患儿均行手术治疗,其中剖腹手术42例(85.7%),腹腔镜手术7例(14.3%);1例腹腔镜手术因胎粪性腹膜炎中转剖腹手术。平均手术时间为(147±43)分钟(70 - 270分钟);术后平均禁食时间为(8±3)天(4 - 16天);平均肠外营养时间为(12±6)天(3 - 30天)。11例患儿术后自动出院失访。其余38例患儿中,1例(2.6%)术后5天因胃肠穿孔行肠切除造瘘术;1例(2.6%)术后1个月因粘连性肠梗阻行保守治疗治愈出院;1例(2.6%)术后8天因吻合口漏行肠透析及回肠造瘘术,3个月后行瘘口关闭术;4例患儿出现水电解质紊乱、贫血、低蛋白血症等并发症,经保守治疗后痊愈。术后随访显示,1例十二指肠闭锁患儿术后6个月体重偏低,1岁时恢复正常;1例32周早产患儿行肠内营养治疗,6个月后逐渐恢复正常饮食。其余患儿未观察到生长发育迟缓。

结论

术中积极治疗并尽可能保留正常肠管,小儿复杂肠闭锁的预后通常良好。

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