Tavassoli F A, Norris H J
Arch Pathol Lab Med. 1986 Nov;110(11):1045-53.
Nine examples of mammary adenoid cystic carcinoma with sebaceous differentiation were studied. Each one of the nine tumors contained basaloid, eosinophilic, and sebaceous cells. Two of these tumors were examined by electron microscopy and compared with four mammary adenoid cystic carcinomas without sebaceous differentiation. The sebaceous cells were similar to normal adnexal sebaceous cells. The eosinophilic cells reflected adenosquamous differentiation and were identical to superficial cells of eccrine sweat ducts. The basaloid cells showed no distinctive cytoplasmic differentiation. Cells with features between the basaloid, sebaceous, and adenosquamous cells were present, indicating that basaloid cells have the potential to differentiate toward skin adnexal structures giving rise to both sebaceous and adenosquamous cells. Myoepithelial cells were not identified in any of the six tumors evaluated by electron microscopy.
对9例伴有皮脂腺分化的乳腺腺样囊性癌进行了研究。这9个肿瘤中的每一个都含有基底样细胞、嗜酸性细胞和皮脂腺细胞。其中2个肿瘤进行了电子显微镜检查，并与4例无皮脂腺分化的乳腺腺样囊性癌进行了比较。皮脂腺细胞与正常附属器皮脂腺细胞相似。嗜酸性细胞反映腺鳞分化，与小汗腺导管的表层细胞相同。基底样细胞未显示出明显的细胞质分化。存在具有基底样、皮脂腺和腺鳞细胞特征之间特征的细胞，这表明基底样细胞有向皮肤附属器结构分化的潜力，可产生皮脂腺细胞和腺鳞细胞。在通过电子显微镜评估的6个肿瘤中均未发现肌上皮细胞。
