Shibata Shoyo, Uemura Ryotaro, Suzuki Takeshi
1 Division of Basic Biological Sciences, Faculty of Pharmacy, Keio University, Tokyo, Japan.
2 Division of Basic Education, Faculty of Pharmacy, Keio University, Tokyo, Japan.
Ther Innov Regul Sci. 2016 Mar;50(2):221-227. doi: 10.1177/2168479015604182.
Japan is currently the second largest pharmaceutical market in the world, and Japanese pharmaceutical companies are actively seeking to identify assets in other countries. An affluent population provides ample opportunity for pharmaceutical companies to develop within Japan; however, given its weak macroeconomic foundation, Japan is currently seeking to cut costs through the use of more generic drugs and lower prices. Nevertheless, no detailed empirical analyses regarding how Japanese companies can expand their global presence while ensuring domestic sales, or what opportunities lie ahead for global companies planning to enter the Japanese market, have been conducted. To our knowledge, this is the first study to provide statistical evidence regarding characteristics of the Japanese market.
The data set for this study was the most recent list of the 100 top-selling drugs globally and in Japan, the United States, the United Kingdom, France, and Germany. The data were obtained from the IMS Japan Pharmaceutical Market database.
More cardiovascular and less central nervous system (CNS) and oncology drugs were ranked among the top 100 best-selling drugs in the Japanese market; however, the promotion of CNS and oncology drug development was evident, and competition from generic drugs was shown to have eroded, especially in therapeutic areas with no assured benefits in the global market, such as with cardiovascular drugs.
These results suggest that the Japanese market will rival overseas markets in the near future. Pharmaceutical companies should seriously consider operating within Japan, whose market is currently transitioning to a global market.
日本目前是世界第二大制药市场,日本制药公司正积极寻求在其他国家寻找资产。富裕的人口为制药公司在日本发展提供了充足的机会;然而,鉴于其薄弱的宏观经济基础,日本目前正寻求通过使用更多仿制药和降低价格来削减成本。尽管如此,尚未有人针对日本公司如何在确保国内销售的同时扩大其全球影响力,或者计划进入日本市场的全球公司面临哪些机遇进行详细的实证分析。据我们所知,这是第一项提供有关日本市场特征统计证据的研究。
本研究的数据集是全球以及日本、美国、英国、法国和德国最畅销的100种药品的最新清单。数据来自IMS日本制药市场数据库。
在日本市场最畅销的100种药品中,心血管药物较多,而中枢神经系统(CNS)药物和肿瘤药物较少;然而,中枢神经系统和肿瘤药物开发的推广很明显,并且仿制药的竞争已显示出侵蚀作用,尤其是在全球市场没有确凿益处的治疗领域,如心血管药物领域。
这些结果表明,日本市场在不久的将来将与海外市场竞争。制药公司应认真考虑在日本开展业务,其市场目前正在向全球市场转型。