a Department of Mechanical Engineering , Newcastle University, School of Engineering , Newcastle upon Tyne , UK.
b Northern Medical Physical and Clinical Engineering department , NHS Foundation Trust , Newcastle upon Tyne , UK.
Expert Rev Med Devices. 2018 Oct;15(10):725-733. doi: 10.1080/17434440.2018.1525291. Epub 2018 Oct 1.
Continuous positive airway pressure (CPAP) therapy is a clinical treatment for moderate or severe obstructive sleep apnea (OSA). Commercial CPAP mask designs normally come in standard sizes and the configuration is not commonly tailored to the patients' characteristics such as face topology, skin sensitivity, and severity of OSA syndrome; however, an optimal mask/interface selection is a key factor influencing the compliance and effectiveness of CPAP treatment.
This review investigates the conventional CPAP mask design, its effect on OSA treatment, and the related risk factors that can lead to skin damage after long-term repeated use. Through a literature search on common databases, Scopus, PubMed, and Google Scholar, we identified reported facts on the influence of the mask interface and current trends toward customized devices.
There is potential for optimizing the CPAP mask fit by adapting the interface to the patients' individual characteristics. This holds particularly true for users with abnormal features or simply outside conventional industry sizing standards. Enabling technologies for undertaking this adaptation include reverse engineering, computational modeling, and additive manufacturing. There is to date no integrated system that integrates those elements into a standard solution, but several studies have shown its effectiveness for specific cohorts.
持续气道正压通气(CPAP)疗法是治疗中重度阻塞性睡眠呼吸暂停(OSA)的一种临床方法。商用 CPAP 面罩设计通常采用标准尺寸,其结构通常不根据患者的特征(如面部拓扑结构、皮肤敏感性和 OSA 综合征的严重程度)进行定制;然而,面罩/接口的最佳选择是影响 CPAP 治疗依从性和效果的关键因素。
本综述研究了传统 CPAP 面罩设计、其对 OSA 治疗的影响,以及长期重复使用后可能导致皮肤损伤的相关风险因素。通过对 Scopus、PubMed 和 Google Scholar 等常见数据库的文献检索,我们确定了关于面罩接口影响的报告事实以及当前向定制设备发展的趋势。
通过使接口适应患者的个体特征,CPAP 面罩的适配性具有优化的潜力。对于具有异常特征或超出常规行业尺寸标准的用户尤其如此。实现这种适应的使能技术包括逆向工程、计算建模和增材制造。目前尚无将这些元素集成到标准解决方案中的集成系统,但已有多项研究表明,对于特定队列,该系统具有有效性。