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《肥胖及相关疾病的外科手术:I. 一种量化纵向声速的新方法及其组织表征潜力》

Surgery for Obesity and Related Diseases: I. A Novel Approach to the Quantification of the Longitudinal Speed of Sound and Its Potential for Tissue Characterization.

作者信息

Benjamin Alex, Zubajlo Rebecca E, Dhyani Manish, Samir Anthony E, Thomenius Kai E, Grajo Joseph R, Anthony Brian W

机构信息

Device Realization and Computational Instrumentation Laboratory, Department of Mechanical Engineering Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

Center for Ultrasound Research and Translation Abdominal Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Internal Medicine, Steward Carney Hospital, Dorchester, Massachusetts, USA.

出版信息

Ultrasound Med Biol. 2018 Dec;44(12):2739-2748. doi: 10.1016/j.ultrasmedbio.2018.07.021. Epub 2018 Sep 15.

DOI:10.1016/j.ultrasmedbio.2018.07.021
PMID:30228044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6662181/
Abstract

Described here is a method to determine the longitudinal speed of sound in speckle-dominated ultrasound images. The method is based on the concept that the quality of an ultrasound image is maximized when the beamformer's speed of sound matches the speed in the medium. The method captures the quality of the ultrasound image using two quantitative image-quality metrics: image brightness and sharpness around the intended focal zone. The proposed method requires no calibration, is computationally efficient and is deployable on commercial ultrasound systems without hardware or software modifications. Ex vivo testing on tissue-mimicking phantoms indicates the method's accuracy in predicting the true speed of sound to within 1% of ground truth values.

摘要

本文描述了一种在散斑主导的超声图像中确定纵向声速的方法。该方法基于这样一个概念:当波束形成器的声速与介质中的声速匹配时,超声图像的质量达到最大化。该方法使用两个定量图像质量指标来捕捉超声图像的质量:预期聚焦区域周围的图像亮度和清晰度。所提出的方法无需校准,计算效率高,并且无需对硬件或软件进行修改即可部署在商用超声系统上。在组织模拟体模上进行的离体测试表明,该方法在预测真实声速方面的准确性可达到与真实值相差在1%以内。

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Phys Med Biol. 2017 May 7;62(9):3582-3598. doi: 10.1088/1361-6560/aa6226. Epub 2017 Feb 22.
2
Quantitative Ultrasound for Staging of Hepatic Steatosis in Patients on Home Parenteral Nutrition Validated with Magnetic Resonance Spectroscopy: A Feasibility Study.定量超声对家庭肠外营养患者肝脂肪变性分期的研究:与磁共振波谱法对比验证的可行性研究
Ultrasound Med Biol. 2016 Mar;42(3):637-44. doi: 10.1016/j.ultrasmedbio.2015.11.004. Epub 2015 Dec 19.
3
Variation of ultrasound image lateral spectrum with assumed speed of sound and true scatterer density.超声图像横向频谱随假定声速和真实散射体密度的变化。
Ultrasonics. 2015 Feb;56:370-80. doi: 10.1016/j.ultras.2014.09.003. Epub 2014 Sep 16.
4
A new method for measuring the speed of sound in rat liver ex vivo using an ultrasound system: correlation of sound speed with fat deposition.一种使用超声系统在离体大鼠肝脏中测量声速的新方法:声速与脂肪沉积的相关性
Ultrasound Med Biol. 2014 Oct;40(10):2499-507. doi: 10.1016/j.ultrasmedbio.2014.03.019. Epub 2014 Aug 15.
5
Ex vivo study of quantitative ultrasound parameters in fatty rabbit livers.兔脂肪肝的超声定量参数的离体研究。
Ultrasound Med Biol. 2012 Dec;38(12):2238-48. doi: 10.1016/j.ultrasmedbio.2012.08.010. Epub 2012 Oct 11.
6
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Int J Comput Assist Radiol Surg. 2012 Nov;7(6):891-9. doi: 10.1007/s11548-012-0690-9. Epub 2012 Apr 28.
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