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消化性溃疡病与感染

Peptic Ulcer Disease and infection.

作者信息

Narayanan Mechu, Reddy Kavya M, Marsicano Elizabeth

机构信息

Mechu Narayanan, MD, is Fellow in the Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, Mo.

Kavya M. Reddy, MD, is Fellow in the Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, Mo.

出版信息

Mo Med. 2018 May-Jun;115(3):219-224.

PMID:30228726
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6140150/
Abstract

Peptic ulcer disease (PUD) is a common condition that both primary care providers and gastroenterologists encounter. Symptoms of peptic ulcer disease are variable and may include abdominal pain, nausea, vomiting, weight loss and bleeding or perforation with complicated disease. Identifying the risk factors and mechanisms that lead to the development of PUD helps to understand the approach behind diagnostic and treatment strategies.

摘要

消化性溃疡病(PUD)是初级保健医生和胃肠病学家都会遇到的常见病症。消化性溃疡病的症状各不相同,可能包括腹痛、恶心、呕吐、体重减轻以及复杂病情时的出血或穿孔。识别导致消化性溃疡病发生的风险因素和机制有助于理解诊断和治疗策略背后的方法。

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本文引用的文献

1
Risk of gastrointestinal bleeding during anticoagulant treatment.抗凝治疗期间胃肠道出血的风险。
Expert Opin Drug Saf. 2017 Jun;16(6):673-685. doi: 10.1080/14740338.2017.1325870. Epub 2017 May 17.
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Peptic ulcer disease.消化性溃疡病。
Lancet. 2017 Aug 5;390(10094):613-624. doi: 10.1016/S0140-6736(16)32404-7. Epub 2017 Feb 25.
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ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.美国胃肠病学会临床指南:幽门螺杆菌感染的治疗
Am J Gastroenterol. 2017 Feb;112(2):212-239. doi: 10.1038/ajg.2016.563. Epub 2017 Jan 10.
4
25 Years of Proton Pump Inhibitors: A Comprehensive Review.质子泵抑制剂的25年:全面综述
Gut Liver. 2017 Jan 15;11(1):27-37. doi: 10.5009/gnl15502.
5
Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report.幽门螺杆菌感染的管理——马斯特里赫特 V/佛罗伦萨共识报告。
Gut. 2017 Jan;66(1):6-30. doi: 10.1136/gutjnl-2016-312288. Epub 2016 Oct 5.
6
Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA.在美国,幽门螺杆菌对克拉霉素耐药及治疗失败的情况很常见。
Dig Dis Sci. 2016 Aug;61(8):2373-2380. doi: 10.1007/s10620-016-4091-8. Epub 2016 Feb 29.
7
Helicobacter-negative gastritis: polymerase chain reaction for Helicobacter DNA is a valuable tool to elucidate the diagnosis.幽门螺杆菌阴性胃炎:聚合酶链反应检测幽门螺杆菌 DNA 是明确诊断的有价值的工具。
Aliment Pharmacol Ther. 2016 Apr;43(8):924-932. doi: 10.1111/apt.13564. Epub 2016 Feb 17.
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Value of the "Test & Treat" Strategy for Uninvestigated Dyspepsia at Low Prevalence Rates of Helicobacter pylori in the Population.“检测与治疗”策略在人群中幽门螺杆菌低流行率情况下对未经调查的消化不良的价值。
Helicobacter. 2016 Jun;21(3):186-91. doi: 10.1111/hel.12267. Epub 2015 Sep 8.
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Risk of upper and lower gastrointestinal bleeding in patients taking nonsteroidal anti-inflammatory drugs, antiplatelet agents, or anticoagulants.服用非甾体抗炎药、抗血小板药物或抗凝剂的患者上消化道和下消化道出血的风险。
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Intermittent vs continuous proton pump inhibitor therapy for high-risk bleeding ulcers: a systematic review and meta-analysis.间断性与持续性质子泵抑制剂治疗高危出血性溃疡:系统评价和荟萃分析。
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