van der Spuy Ina, Zhao Gaungming, Karunanayake Chandima, Pahwa Punam
School of Rehabilitation Science, College of Medicine, University of Saskatchewan, 104 Clinic Place, Saskatoon, Saskatchewan, Canada S7N 2Z4.
Canadian Centre for Health and Safety in Agriculture, University of Saskatchewan, 104 Clinic Place, Saskatoon, Saskatchewan, Canada S7N 2Z4.
Can Respir J. 2018 Aug 28;2018:6349790. doi: 10.1155/2018/6349790. eCollection 2018.
Older age, obesity, hypertension, snoring, and excessive daytime sleepiness have been associated with sleep apnea. The objective of this study was to determine the prevalence (crude and adjusted), as well as the risk factors, of sleep apnea in the adult Canadian population. Data from the 2009 Sleep Apnea Rapid Response (SARR) questionnaire were used to identify the risk factors, and all sleep-related questions in the SARR questionnaire were used. The outcome variable of interest was health professional-diagnosed sleep apnea. Covariates of interest were demographic variables, population characteristics, respiratory and cardiovascular diseases, and enabling resources. The multiple logistic regression model adjusted for the clustering effect was used to analyze the data. Sleep apnea was diagnosed in 858,913 adults (3.4% of the population), and more men (65.4%) than women (34.6%) were diagnosed with sleep apnea. Multivariable logistic regression analysis indicated that age (45 and older), loud snoring, sudden awakening with gasping/choking (rare/sometimes and once or more a week), and nodding off/falling asleep in driving in the past 12 months were significantly associated with diagnosed sleep apnea. Predictive probability demonstrated that in overweight and obese persons, ≥15 minutes of daily exercise significantly decreased the risk of diagnosed sleep apnea. The conclusion of this study is that in the Canadian population, sleep apnea is associated with older age, loud snoring, and sleeping problems. The protective effect of exercise warrants further investigation.
年龄较大、肥胖、高血压、打鼾以及白天过度嗜睡都与睡眠呼吸暂停有关。本研究的目的是确定加拿大成年人群中睡眠呼吸暂停的患病率(粗患病率和校正患病率)及其风险因素。利用2009年睡眠呼吸暂停快速反应(SARR)问卷的数据来确定风险因素,且使用了SARR问卷中所有与睡眠相关的问题。感兴趣的结果变量是由健康专业人员诊断的睡眠呼吸暂停。感兴趣的协变量包括人口统计学变量、人群特征、呼吸和心血管疾病以及可用资源。使用针对聚类效应进行校正的多元逻辑回归模型来分析数据。858,913名成年人被诊断为睡眠呼吸暂停(占总人口的3.4%),被诊断为睡眠呼吸暂停的男性(65.4%)多于女性(34.6%)。多变量逻辑回归分析表明,年龄(45岁及以上)、大声打鼾、因喘气/窒息突然醒来(很少/有时以及每周一次或多次)以及在过去12个月内开车时打瞌睡/睡着与确诊的睡眠呼吸暂停显著相关。预测概率表明,超重和肥胖者每天进行≥15分钟的锻炼可显著降低确诊睡眠呼吸暂停的风险。本研究的结论是,在加拿大人群中,睡眠呼吸暂停与年龄较大、大声打鼾和睡眠问题有关。运动的保护作用值得进一步研究。