心血管和免疫变量对患有抗磷脂抗体的受试者亚临床颈动脉粥样硬化的影响。
Impact of cardiovascular and immunologic variables on subclinical carotid atherosclerosis in subjects with anti-phospholipid antibodies.
作者信息
Di Minno Matteo Nicola Dario, Emmi Giacomo, Ambrosino Pasquale, Scalera Antonella, Tufano Antonella, Cafaro Giovanni, Peluso Rosario, Bettiol Alessandra, Di Scala Gerardo, Silvestri Elena, Prisco Domenico
机构信息
Department of Translational Medical Sciences, Federico II University, Naples, Italy.
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
出版信息
Data Brief. 2018 Jun 27;19:1799-1803. doi: 10.1016/j.dib.2018.06.083. eCollection 2018 Aug.
Whereas some previous data on carriers with isolated antiphospholipid antibodies positivity (APP) suggested an increased risk of arterial events in this clinical setting, no data are available on subclinical atherosclerosis in this clinical setting. This article reports data on intima-media thickness of the common carotid artery (CCA-IMT) and of the Bulb (Bulb-IMT) and on the prevalence of carotid plaques in APP carriers and in subjects with antiphospholipid syndrome (APS) specifically stratifying for the presence of thrombotic manifestations, cardiovascular risk factors, antibody isotype and concomitant Systemic Lupus Erythematosus (SLE) or other autoimmune diseases.
尽管先前一些关于孤立性抗磷脂抗体阳性（APP）携带者的数据表明，在此临床情况下动脉事件风险增加，但关于此临床情况下亚临床动脉粥样硬化的数据尚无可用。本文报告了APP携带者和抗磷脂综合征（APS）患者的颈总动脉内膜中层厚度（CCA-IMT）和球部（球部-IMT）以及颈动脉斑块患病率的数据，具体根据血栓形成表现、心血管危险因素、抗体亚型以及是否合并系统性红斑狼疮（SLE）或其他自身免疫性疾病进行分层。
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