Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, People's Republic of China,
National Clinical Research Center for Geriatrics, West China Hospital, Chengdu 610041, People's Republic of China,
Clin Interv Aging. 2018 Sep 5;13:1605-1611. doi: 10.2147/CIA.S173146. eCollection 2018.
The aim of this study was to assess the prevalence of sarcopenia and depressive symptoms and estimate the association between them in elderly Chinese community-dwelling individuals.
A total of 948 elderly Chinese community-dwelling individuals were recruited through leaflets and posters from three communities in Chengdu, and 865 participants were analyzed in this cross-sectional study. Muscle mass was measured using the bioimpedance analysis, handgrip strength was measured with a handheld dynamometer, and physical performance was assessed via usual gait speed on a 6 m course. Sarcopenia was defined according to the recommended diagnostic algorithm of the Asia Working Group for Sarcopenia (AWGS). Depressive symptoms were assessed using the Chinese version of 15-item Geriatric Depression Scale (GDS-15) with a score of ≥5 indicative of the presence of depressive symptoms.
A total of 865 participants were included in the analysis. The participants had a mean age of 68.68±6.46 years. Sixty-one (7.1%) participants and 71 (8.2%) participants were identified as having sarcopenia and depressive symptoms, respectively. After adjusting for age, sex, and other potential confounders, sarcopenia was found to be significantly associated with depressive symptoms (odds ratio [OR]: 2.23, 95% CI 1.06-4.92).
The prevalence rates of sarcopenia and depressive symptoms were 7.1 and 8.2%, respectively, in elderly Chinese community-dwelling individuals, and sarcopenia was significantly associated with depressive symptoms.
本研究旨在评估老年中国社区居民中肌少症和抑郁症状的患病率，并评估两者之间的关联。
通过在成都三个社区的传单和海报共招募了 948 名老年中国社区居民，本横断面研究分析了 865 名参与者。使用生物电阻抗分析法测量肌肉质量，使用手持测力计测量握力，通过 6 米常速步行评估身体机能。肌少症根据亚洲肌少症工作组（AWGS）的推荐诊断算法定义。使用 15 项老年抑郁量表（GDS-15）的中文版评估抑郁症状，得分≥5 表明存在抑郁症状。
共纳入 865 名参与者。参与者的平均年龄为 68.68±6.46 岁。61 名（7.1%）和 71 名（8.2%）参与者分别被确定为患有肌少症和抑郁症状。调整年龄、性别和其他潜在混杂因素后，肌少症与抑郁症状显著相关（比值比[OR]：2.23，95%置信区间 1.06-4.92）。
老年中国社区居民中肌少症和抑郁症状的患病率分别为 7.1%和 8.2%，肌少症与抑郁症状显著相关。
