Klebanov Nikolai, Hoang Mai P, Reddy Bobby Y
Dermatology, Massachusetts General Hospital, Boston, USA.
Pathology, Massachusetts General Hospital/Harvard Medical School, Boston, USA.
Cureus. 2018 Jul 13;10(7):e2979. doi: 10.7759/cureus.2979.
Pleomorphic dermal sarcoma (PDS) is a rare mesenchymal tissue tumor. Distinguishing PDS from similar conditions, such as atypical fibroxanthoma (AFX), its less aggressive tumor counterpart, is difficult, as they are clinically and histologically similar. We present a case of a 77-year-old man presenting with a large nodular scalp lesion of three weeks duration. Pathology revealed a 3.3 cm invasive pleomorphic dermal sarcoma. Surgical excision with 2 cm margins was performed with successful healing of the graft. This case highlights a rare case of a large pleomorphic dermal sarcoma and discusses the histological features and management of PDS.
多形性皮肤肉瘤（PDS）是一种罕见的间叶组织肿瘤。将PDS与类似情况（如非典型纤维黄色瘤（AFX），其侵袭性较低的肿瘤对应物）区分开来很困难，因为它们在临床和组织学上相似。我们报告一例77岁男性，其头皮出现一个持续三周的大结节性病变。病理检查显示为3.3厘米的侵袭性多形性皮肤肉瘤。进行了切缘为2厘米的手术切除，移植部位成功愈合。本病例突出了一例罕见的大型多形性皮肤肉瘤，并讨论了PDS的组织学特征和治疗方法。
