三氧化二砷治疗急性早幼粒细胞白血病后继发多发性 Bowen 病和基底细胞癌 1 例并光动力治疗有效

Multiple Bowen's diseases and basal cell carcinomas in a patient with acute promyelocytic leukemia treated with arsenic trioxide: A case report and effective treatment with photodynamic therapy.

机构信息

Department of Dermatology, Third People's Hospital of Hangzhou Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.

出版信息

Dermatol Ther. 2018 Nov;31(6):e12718. doi: 10.1111/dth.12718. Epub 2018 Sep 21.

DOI:10.1111/dth.12718

PMID:30239071

Abstract

It is very rare that multiple Bowen's disease (BD) and basal cell carcinoma (BCC) lesions develop in a single patient. Routine therapy for the multiple lesions is not satisfactory. The present authors report on a patient who had developed multiple BD and BCC lesions for 12 years after arsenic trioxide treatment for his acute promyelocytic leukemia 20 years before. The patient with multiple lesions was successfully treated with photodynamic therapy.

摘要

多发性 Bowen 病（BD）和基底细胞癌（BCC）在单个患者中同时发生的情况非常罕见。对于多发性病变，常规治疗效果并不理想。本文报道了 1 例患者，在 20 年前因急性早幼粒细胞白血病接受三氧化二砷治疗后，12 年内出现多发性 BD 和 BCC 病变。该患者采用光动力疗法成功治疗了多发性病变。