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HPV 疫苗推广中最有用的工具是什么?一项实验研究的结果。

What is the most useful tool in HPV vaccine promotion? Results from an experimental study.

机构信息

a Department of Public Health, University of Torino , Torino , Italy.

出版信息

Hum Vaccin Immunother. 2019;15(7-8):1607-1614. doi: 10.1080/21645515.2018.1526552. Epub 2018 Oct 5.

Abstract

: Human papillomavirus infection (HPV) affects 70-80% of female population throughout the lifetime, exposing them to the risk of developing genital warts and cervical cancer. Despite these correlated risks and the demonstrated efficacy of the vaccine, coverage rates for two-three doses are around 70% in Italy and 67% in Piemonte (below the expected 95%). Aim of the study is to investigate whether this situation is due to a lack of information and awareness among young adults. : Students showed increased knowledge after the intervention and more than 90% found the 3 informative materials as sources of useful information. After the intervention students would strongly recommend HPV vaccination (OR = 3.45; p < 0.001). : Higher rates of correct answers after the distribution of informative material underline the importance of knowledge delivery. Differences among the kind of material were reported; it appears that a combination of leaflet's positive features, such as clarity and intelligibility, and article's completeness of information represents the best solution to reach communication goals in vaccination campaigns targeted on educated populations. : Researchers conducted an experimental study on a large population of undergraduate students from University of Turin. Participants' knowledge about HPV was assessed with questionnaires before and after the examination of 3 different kinds of informative material (journal article describing HPV infection, gynecologist video-interview and institutional leaflet about HPV prevention) on HPV and vaccine. Differences among groups were explored by using univariate tests, differences in pre- post- knowledge were assessed with McNemar tests. Relevant associations were searched with logistic regression models.

摘要

: 人乳头瘤病毒感染(HPV)会影响一生中 70-80%的女性群体,使她们面临患生殖器疣和宫颈癌的风险。尽管存在这些相关风险,且疫苗已被证实有效,但意大利和皮埃蒙特(Piemonte)的两到三剂疫苗接种率分别约为 70%和 67%(低于预期的 95%)。本研究旨在探究这种情况是否是由于年轻人缺乏信息和意识所致。 : 干预后,学生的知识有所增加,超过 90%的学生认为三种信息材料是有用信息的来源。干预后,学生将强烈推荐 HPV 疫苗接种(OR=3.45;p<0.001)。 : 信息材料分发后,正确答案的比例有所提高,这强调了知识传递的重要性。不同类型的材料之间存在差异;似乎在针对受教育人群的疫苗接种宣传活动中,将传单的积极特征(如清晰易懂)与文章的完整信息相结合,是实现传播目标的最佳解决方案。 : 研究人员对都灵大学的一大群本科生进行了一项实验研究。在对 HPV 和疫苗的三种不同信息材料(描述 HPV 感染的期刊文章、妇科医生视频采访和关于 HPV 预防的机构传单)进行检查之前和之后,使用问卷评估参与者对 HPV 的了解程度。使用单变量检验探索组间差异,使用 McNemar 检验评估知识的前后差异。使用逻辑回归模型搜索相关关联。

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