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坚持素食可能会增加老年男性中国人群出现抑郁症状的风险。

Adhering to a vegetarian diet may create a greater risk of depressive symptoms in the elderly male Chinese population.

机构信息

Lu'an Municipal Center for Disease Control and Prevention, Anhui Lu'an 237000, China.

Lu'an Municipal Center for Disease Control and Prevention, Anhui Lu'an 237000, China.

出版信息

J Affect Disord. 2019 Jan 15;243:182-187. doi: 10.1016/j.jad.2018.09.033. Epub 2018 Sep 17.

DOI:10.1016/j.jad.2018.09.033
PMID:30243198
Abstract

BACKGROUND

A vegetarian diet may be a risk factor for depression, but this relationship was unclear in the elderly Chinese population.

METHODS

Self-report data were gathered from 1051 elderly persons using the Cohort of Elderly Health and Environment Controllable Factors, which was created in West Anhui, China. The depressive symptoms were set as binary, ordinal, and continuous outcomes, respectively, whereas the dietary structures were computed as an ordinal variable and a dummy variable. Multiple logistic regression, ordinal regression, and linear regression were used to assess the relationship by adjusting the potential confounding variables with p-values of <0.1 in univariate analysis.

RESULTS

The elderly participants who had a vegetable-based diet had the highest GDS scores of 8.78 ± 6.894 (p = 0.001) and the highest rate of depression (32.9%, p = 0.003). After adjustment for the potential confounders, elderly men who had a vegetable-based diet had a higher rate of depression (OR[95%CI]: 1.62[1.07-2.46], 4.71[1.38-16.03]), more severe symptoms of depression (OR[95%CI]: 8.85[2.94-34.12]), and higher GDS scores (β[95%CI]: 1.46[0.70-2.22], 2.97[1.28-4.67]) than male participants who had a meat-based diet, but this was not the case in women.

LIMITATIONS

All data were self-reported. The study lacked quantitatively evaluated dietary intake. The duration of the current dietary structures and comorbidities were not reported. The cross-sectional study made the causal role uncertain.

CONCLUSIONS

Vegetarian diets may pose a greater risk of depressive symptoms among the elderly Chinese population, especially elderly men. Given the cross-sectional nature of this study, the causal role was uncertain. Further prospective studies, in particular among elderly women, are needed.

摘要

背景

素食可能是老年人抑郁的一个风险因素,但这种关系在中国老年人中并不明确。

方法

使用中国西部安徽的老年健康与环境可控因素队列,收集了 1051 名老年人的自我报告数据。抑郁症状分别设定为二分类、有序和连续结局,而饮食结构则计算为有序变量和虚拟变量。采用多因素逻辑回归、有序回归和线性回归,对潜在混杂因素进行调整,在单因素分析中 p 值<0.1 的变量纳入分析。

结果

素食饮食的老年人 GDS 评分最高为 8.78±6.894(p=0.001),抑郁发生率最高为 32.9%(p=0.003)。调整潜在混杂因素后,素食饮食的老年男性抑郁发生率更高(OR[95%CI]:1.62[1.07-2.46],4.71[1.38-16.03]),抑郁症状更严重(OR[95%CI]:8.85[2.94-34.12]),GDS 评分更高(β[95%CI]:1.46[0.70-2.22],2.97[1.28-4.67]),而肉食饮食的老年男性则没有这种情况,但在女性中则不然。

局限性

所有数据均为自我报告,研究缺乏定量评估的饮食摄入,未报告当前饮食结构和并存疾病的持续时间,横断面研究不能确定因果关系。

结论

素食可能会增加中国老年人,尤其是老年男性患抑郁症状的风险。由于本研究为横断面研究,因果关系尚不确定。需要进一步开展前瞻性研究,特别是针对老年女性的研究。

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