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Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development.
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A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction.
J Hepatol. 2017 Oct;67(4):669-679. doi: 10.1016/j.jhep.2017.05.010. Epub 2017 May 18.
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Advances and Challenges in Studying Hepatitis B Virus In Vitro.
Viruses. 2016 Jan 14;8(1):21. doi: 10.3390/v8010021.
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Animal models for the study of hepatitis B virus infection.
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Small animal model systems for studying hepatitis B virus replication and pathogenesis.
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[From the Establishment of Hepatitis B Virus Cell Culture Systems to Drug Discovery].
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Mouse models of hepatitis B and delta virus infection.
J Immunol Methods. 2014 Aug;410:39-49. doi: 10.1016/j.jim.2014.03.002. Epub 2014 Mar 12.
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Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection.
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Therapeutic Nanomaterials in NAFLD: Current Advances and Potential Applications in Patients with Concurrent HBV Infection.
Int J Nanomedicine. 2025 Mar 25;20:3803-3823. doi: 10.2147/IJN.S510271. eCollection 2025.
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Modeling of hepatitis B virus infection spread in primary human hepatocytes.
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Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome.
PLoS Pathog. 2025 Jan 3;21(1):e1012824. doi: 10.1371/journal.ppat.1012824. eCollection 2025 Jan.
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Long-term 3D cell culture models for hepatitis B virus studies.
Virology. 2024 Dec;600:110265. doi: 10.1016/j.virol.2024.110265. Epub 2024 Oct 18.
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The feasibility of establishing a hamster model for HBV infection: evidence.
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The loss of hepatitis B virus receptor NTCP/SLC10A1 in human liver cancer cells is due to epigenetic silencing.
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The Application of Organoids in the Study of Antiviral Innate Immunity.
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De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry.
Cell Chem Biol. 2018 Jul 19;25(7):906-915.e5. doi: 10.1016/j.chembiol.2018.04.011. Epub 2018 May 17.
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A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction.
Biochem Biophys Res Commun. 2018 Jun 22;501(2):374-379. doi: 10.1016/j.bbrc.2018.04.187. Epub 2018 May 11.
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Inhibitory effect of fasiglifam on hepatitis B virus infections through suppression of the sodium taurocholate cotransporting polypeptide.
Biochem Biophys Res Commun. 2018 Jun 27;501(3):820-825. doi: 10.1016/j.bbrc.2018.04.199. Epub 2018 May 4.
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Establishment of Cre-mediated HBV recombinant cccDNA (rcccDNA) cell line for cccDNA biology and antiviral screening assays.
Antiviral Res. 2018 Apr;152:45-52. doi: 10.1016/j.antiviral.2018.02.007. Epub 2018 Feb 9.
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A novel hepatitis B virus species discovered in capuchin monkeys sheds new light on the evolution of primate hepadnaviruses.
J Hepatol. 2018 Jun;68(6):1114-1122. doi: 10.1016/j.jhep.2018.01.029. Epub 2018 Feb 8.
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The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation.
PLoS Pathog. 2017 Dec 29;13(12):e1006784. doi: 10.1371/journal.ppat.1006784. eCollection 2017 Dec.
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Genomic and Proteomic Resolution of Heterochromatin and Its Restriction of Alternate Fate Genes.
Mol Cell. 2017 Dec 21;68(6):1023-1037.e15. doi: 10.1016/j.molcel.2017.11.030.

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