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结肠黏膜施万细胞瘤病例及罕见结肠息肉文献综述

Case of colonic mucosal Schwann cell hamartoma and review of literature on unusual colonic polyps.

作者信息

Chintanaboina JayaKrishna, Clarke Kofi

机构信息

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.

出版信息

BMJ Case Rep. 2018 Sep 21;2018:bcr-2018-224931. doi: 10.1136/bcr-2018-224931.

Abstract

Mucosal Schwann cell hamartomas (MSCH) are benign mesenchymal tumours rarely seen in the gastrointestinal tract. They occasionally present as incidental sessile polyps during colonoscopy. A 55-year-old asymptomatic female patient with a medical history of multiple sclerosis presented for a screening colonoscopy. A 5 mm low-risk tubular adenoma was noted in the caecum, and a second 5 mm polyp was found in the ascending colon. Histopathology of the ascending colon polyp showed proliferation of spindle cells without ganglion cells in the lamina propria. Immunohistochemical findings are compatible with an MSCH. Surveillance colonoscopy was scheduled in 5 years based on the presence of a single low-risk tubular adenoma.

摘要

黏膜施万细胞瘤(MSCH)是一种罕见于胃肠道的良性间叶组织肿瘤。它们偶尔在结肠镜检查时作为偶然发现的无蒂息肉出现。一名55岁无症状女性患者,有多发性硬化病史,前来进行结肠镜筛查。在盲肠发现一个5毫米的低风险管状腺瘤,在升结肠发现另一个5毫米的息肉。升结肠息肉的组织病理学显示固有层梭形细胞增殖,无神经节细胞。免疫组化结果与MSCH相符。鉴于存在单个低风险管状腺瘤,计划在5年后进行结肠镜监测。

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