Saleem Abdulmalik, Jamali Taher, Gueorguieva Iana
Department of Internal Medicine, Henry Ford Hospital, Detroit, MI.
Department of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.
ACG Case Rep J. 2025 May 21;12(5):e01708. doi: 10.14309/crj.0000000000001708. eCollection 2025 May.
Mucosal Schwann cell hamartomas (MSCH) are rare benign tumors typically found in the colorectal region. We present the case of an 87-year-old man with a history of mucosa-associated lymphoid tissue lymphoma who developed symptomatic gastrointestinal bleeding due to an appendiceal MSCH. The patient's ongoing melena and anemia led to further evaluation. Subsequent colonoscopy revealed active bleeding from the appendiceal orifice with hemostasis achieved using epinephrine injection. A laparoscopic appendectomy confirmed MSCH through histopathology and immunohistochemical staining. Given its rarity, this case underscores the importance of considering MSCH in unexplained gastrointestinal bleeding and demonstrates its potential to be a symptomatically significant entity.
黏膜施万细胞瘤（MSCH）是罕见的良性肿瘤，通常见于结直肠区域。我们报告一例87岁男性病例，该患者有黏膜相关淋巴组织淋巴瘤病史，因阑尾MSCH出现有症状的胃肠道出血。患者持续的黑便和贫血促使进一步评估。随后的结肠镜检查显示阑尾开口处有活动性出血，通过注射肾上腺素实现了止血。腹腔镜阑尾切除术通过组织病理学和免疫组化染色确诊为MSCH。鉴于其罕见性，该病例强调了在不明原因的胃肠道出血中考虑MSCH的重要性，并证明其可能是一个有显著症状的实体。
