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极低出生体重早产儿胎粪梗阻的预防

Prevention of meconium obstruction in very low birth weight preterm infants.

作者信息

Solaz-García A J, Segovia-Navarro L, Rodríguez de Dios-Benlloch J L, Benavent-Taengua L, Castilla-Rodríguez D Y, Company-Morenza M A

机构信息

Unidad de Cuidados Intensivos Neonatales, Servicio de Neonatología, Hospital Universitario y Politécnico La Fe, Valencia, España.

Unidad de Cuidados Intensivos Neonatales, Servicio de Neonatología, Hospital Universitario y Politécnico La Fe, Valencia, España.

出版信息

Enferm Intensiva (Engl Ed). 2019 Apr-Jun;30(2):72-77. doi: 10.1016/j.enfi.2018.06.002. Epub 2018 Sep 20.

Abstract

INTRODUCTION

Delayed meconium expulsion is a cause of bowel obstruction in the extremely premature newborn (<28 WGE) weighing less than 1500g at birth.

OBJECTIVE

To evaluate the efficacy of conservative treatment in the prevention of meconium obstruction in very-low-birt- weight preterm infants.

METHOD

Descriptive and retrospective study performed at the Neonatal Intensive Care Unit of a tertiary level hospital. All very-low-birth-weight preterm infants who were born during the study period, from August 2016 to January 2017, and who had meconium obstruction were included.

RESULTS

A sample of 42 newborn infants was obtained. Regarding the expulsion of meconium, 57.1% of the sample spontaneously ejected meconium, while 42.9% received different treatments. Of these, 72.2% were treated with saline enemas, 16% with acetylcysteine enemas, 16% with Gastrografin and none required surgical treatment.

CONCLUSION

Conservative treatment seems to be an effective therapeutic measure for the prevention of meconium obstruction in very-low-birth-weight preterm infants since it achieved the expulsion of meconium without having to apply surgical treatment.

摘要

引言

胎粪排出延迟是出生时体重小于1500克的极早产儿(<28周孕龄)肠梗阻的一个原因。

目的

评估保守治疗在预防极低出生体重早产儿胎粪梗阻中的疗效。

方法

在一家三级医院的新生儿重症监护病房进行描述性和回顾性研究。纳入2016年8月至2017年1月研究期间出生且患有胎粪梗阻的所有极低出生体重早产儿。

结果

获得了42例新生儿样本。关于胎粪排出情况,57.1%的样本自行排出胎粪,而42.9%接受了不同治疗。其中,72.2%接受盐水灌肠治疗,16%接受乙酰半胱氨酸灌肠治疗,16%接受泛影葡胺治疗,无一例需要手术治疗。

结论

保守治疗似乎是预防极低出生体重早产儿胎粪梗阻有效治疗措施,因为它无需手术治疗即可实现胎粪排出。

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Prevention of meconium obstruction in very low birth weight preterm infants.极低出生体重早产儿胎粪梗阻的预防
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Delayed meconium passage in very low birth weight infants.极低出生体重儿胎粪排出延迟
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