• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

极低出生体重早产儿胎粪梗阻的预防

Prevention of meconium obstruction in very low birth weight preterm infants.

作者信息

Solaz-García A J, Segovia-Navarro L, Rodríguez de Dios-Benlloch J L, Benavent-Taengua L, Castilla-Rodríguez D Y, Company-Morenza M A

机构信息

Unidad de Cuidados Intensivos Neonatales, Servicio de Neonatología, Hospital Universitario y Politécnico La Fe, Valencia, España.

Unidad de Cuidados Intensivos Neonatales, Servicio de Neonatología, Hospital Universitario y Politécnico La Fe, Valencia, España.

出版信息

Enferm Intensiva (Engl Ed). 2019 Apr-Jun;30(2):72-77. doi: 10.1016/j.enfi.2018.06.002. Epub 2018 Sep 20.

DOI:10.1016/j.enfi.2018.06.002
PMID:30245147
Abstract

INTRODUCTION

Delayed meconium expulsion is a cause of bowel obstruction in the extremely premature newborn (<28 WGE) weighing less than 1500g at birth.

OBJECTIVE

To evaluate the efficacy of conservative treatment in the prevention of meconium obstruction in very-low-birt- weight preterm infants.

METHOD

Descriptive and retrospective study performed at the Neonatal Intensive Care Unit of a tertiary level hospital. All very-low-birth-weight preterm infants who were born during the study period, from August 2016 to January 2017, and who had meconium obstruction were included.

RESULTS

A sample of 42 newborn infants was obtained. Regarding the expulsion of meconium, 57.1% of the sample spontaneously ejected meconium, while 42.9% received different treatments. Of these, 72.2% were treated with saline enemas, 16% with acetylcysteine enemas, 16% with Gastrografin and none required surgical treatment.

CONCLUSION

Conservative treatment seems to be an effective therapeutic measure for the prevention of meconium obstruction in very-low-birth-weight preterm infants since it achieved the expulsion of meconium without having to apply surgical treatment.

摘要

引言

胎粪排出延迟是出生时体重小于1500克的极早产儿(<28周孕龄)肠梗阻的一个原因。

目的

评估保守治疗在预防极低出生体重早产儿胎粪梗阻中的疗效。

方法

在一家三级医院的新生儿重症监护病房进行描述性和回顾性研究。纳入2016年8月至2017年1月研究期间出生且患有胎粪梗阻的所有极低出生体重早产儿。

结果

获得了42例新生儿样本。关于胎粪排出情况,57.1%的样本自行排出胎粪,而42.9%接受了不同治疗。其中,72.2%接受盐水灌肠治疗,16%接受乙酰半胱氨酸灌肠治疗,16%接受泛影葡胺治疗,无一例需要手术治疗。

结论

保守治疗似乎是预防极低出生体重早产儿胎粪梗阻有效治疗措施,因为它无需手术治疗即可实现胎粪排出。

相似文献

1
Prevention of meconium obstruction in very low birth weight preterm infants.极低出生体重早产儿胎粪梗阻的预防
Enferm Intensiva (Engl Ed). 2019 Apr-Jun;30(2):72-77. doi: 10.1016/j.enfi.2018.06.002. Epub 2018 Sep 20.
2
Clinical and growth outcomes after meconium-related ileus improved with Gastrografin enema in very low birth weight infants.胃影葡胺灌肠治疗极低出生体重儿胎粪性肠梗阻的临床疗效及生长转归
PLoS One. 2022 Aug 11;17(8):e0272915. doi: 10.1371/journal.pone.0272915. eCollection 2022.
3
Ultrasound-guided contrast enema for meconium obstruction in very low birth weight infants: Factors that affect treatment success.超声引导下对比剂灌肠治疗极低出生体重儿胎粪性肠梗阻:影响治疗成功的因素
Eur J Radiol. 2015 Oct;84(10):2024-31. doi: 10.1016/j.ejrad.2015.06.006. Epub 2015 Jun 7.
4
Small volume enemas do not accelerate meconium evacuation in very low birth weight infants.小剂量灌肠剂并不能加速极低出生体重儿的胎粪排出。
J Pediatr Gastroenterol Nutr. 2007 Feb;44(2):270-3. doi: 10.1097/MPG.0b013e31802c685a.
5
Saline Enemas versus Glycerin Suppositories to Promote Enteral Feeding in Premature Infants: A Pilot Randomized Controlled Trial.生理盐水灌肠剂与甘油栓促进早产儿肠内喂养的比较:一项试点随机对照试验
Neonatology. 2017;112(4):347-353. doi: 10.1159/000477999. Epub 2017 Aug 3.
6
Meconium obstruction in extremely low-birth-weight neonates: guidelines for diagnosis and management.极低出生体重儿胎粪性肠梗阻:诊断与管理指南
J Pediatr Surg. 2004 May;39(5):731-7. doi: 10.1016/j.jpedsurg.2004.01.027.
7
Meconium obstruction in absence of cystic fibrosis in low birth weight infants: an emerging challenge from increasing survival.低体重儿中无囊性纤维化的胎粪性肠梗阻:存活率增加带来的新挑战。
Ital J Pediatr. 2011 Nov 14;37:55. doi: 10.1186/1824-7288-37-55.
8
Meconium obstruction in the very low birth weight premature infant.极低出生体重早产儿的胎粪梗阻
Pediatrics. 2004 Jul;114(1):285-90. doi: 10.1542/peds.114.1.285.
9
Meconium diseases in infants with very low birth weight.极低出生体重儿的胎粪疾病
Semin Pediatr Surg. 2000 May;9(2):79-83. doi: 10.1016/s1055-8586(00)70020-5.
10
Delayed meconium passage in very low birth weight infants.极低出生体重儿胎粪排出延迟
Eur J Pediatr Surg. 2011 Dec;21(6):395-8. doi: 10.1055/s-0031-1291301. Epub 2011 Dec 14.

引用本文的文献

1
Use of N-Acetylcysteine in Preterm Neonates with Enteral Feeding Intolerance and Intestinal Obstruction: A Case Series and Review of the Literature.N-乙酰半胱氨酸在患有肠内喂养不耐受和肠梗阻的早产儿中的应用:病例系列及文献综述
Children (Basel). 2024 Jul 18;11(7):873. doi: 10.3390/children11070873.
2
Breast Milk Enema and Meconium Evacuation Among Preterm Infants: A Randomized Clinical Trial.母乳灌肠和胎粪清除在早产儿中的应用:一项随机临床试验。
JAMA Netw Open. 2024 Apr 1;7(4):e247145. doi: 10.1001/jamanetworkopen.2024.7145.
3
Interventions for Promoting Meconium Passage in Very Preterm Infants-A Survey of Current Practice at Tertiary Neonatal Centers in Germany.
促进极早产儿胎粪排出的干预措施——德国三级新生儿中心当前实践调查
Children (Basel). 2022 Jul 27;9(8):1122. doi: 10.3390/children9081122.
4
Clinical effects of breast milk enema on meconium evacuation in premature infants: study protocol for a randomized controlled trial.母乳灌肠对早产儿胎粪排出的临床效果:一项随机对照试验的研究方案。
Trials. 2021 Apr 26;22(1):304. doi: 10.1186/s13063-021-05261-1.