Loyau G, Pujol J P
Ann Biol Clin (Paris). 1986;44(3):275-80.
An important role is supposed to be played by the collagenases in the physiological or pathological degradation of collagen. However, their exact effects in rheumatic diseases, especially in rheumatoid arthritis is still controversial. The aim of the authors is to give facts and datas up to date, about this important question of the pathogenic role of collagenases in rheumatoid arthritis, osteoarthritis and in several other rheumatic diseases.
胶原酶在胶原蛋白的生理或病理降解过程中应发挥重要作用。然而,它们在风湿性疾病,尤其是类风湿性关节炎中的确切作用仍存在争议。作者的目的是提供关于胶原酶在类风湿性关节炎、骨关节炎及其他几种风湿性疾病中致病作用这一重要问题的最新事实和数据。