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阿尔及尔报告的女性发热性自然流产感染情况。

infection with women's febrile spontaneous abortion reported in Algiers.

作者信息

Ghaoui H, Bitam I, Ait-Oudhia K, Achour N, Saad-Djaballah A, Saadnia F Z, Kedjour S, Fournier P-E, Raoult D

机构信息

IRD, MEPHI, Aix-Marseille Université, IHU Méditerranée Infection, Marseille, France.

École Nationale Supérieure Vétérinaire d'Alger, RABIE BOUCHAMA, Alger, Algérie.

出版信息

New Microbes New Infect. 2018 Aug 11;26:8-14. doi: 10.1016/j.nmni.2018.08.003. eCollection 2018 Nov.

Abstract

We investigated Q fever infection in Febrile Spontaneous Abortions in women by using a serologic method (Immuno-Fluorescence Assay, IFA) and a molecular method (real-time quantitative PCR, qPCR) in Obstetric-Gynaecology (OB-GYN) services in two hospitals in Algiers. We included in the case group 380 women who experienced Febrile Spontaneous Abortion; the control group comprised 345 women who gave birth without any other infections or complications. Among the 725 women included, antibodies against were detected by IFA in three (03) cases patients; all control group samples were IFA negative. In other hand, only four (04) placental samples among the case group came back with q PCR positive for IS1111 and IS30a too. A relationship between infection and febrile spontaneous abortion exists in OB-GYN services in Algiers.

摘要

我们通过血清学方法(免疫荧光测定法,IFA)和分子方法(实时定量PCR,qPCR),对阿尔及尔两家医院妇产科服务中发热性自然流产女性的Q热感染情况进行了调查。病例组纳入了380例经历发热性自然流产的女性;对照组由345例未发生任何其他感染或并发症而分娩的女性组成。在纳入的725名女性中,通过IFA在3例(03)病例患者中检测到了针对[此处原文缺失相关抗原信息]的抗体;所有对照组样本IFA均为阴性。另一方面,病例组中仅有4份(04)胎盘样本qPCR检测IS1111和IS30a也呈阳性。在阿尔及尔的妇产科服务中,[此处原文缺失相关病原体信息]感染与发热性自然流产之间存在关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e6d/6141670/5dd2459651b2/gr1.jpg

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