Simonini Alessandro, Brogi Etrusca, Gily Brunella, Tosca Mariangela, Barbieri Claudia, Antonini Francesca, Del Zotto Genny
Department of Anaesthesia and Intensive Care, Istituto Giannina Gaslini, Genova, Italy.
Department of Anesthesia and Intensive Care, University of Pisa, Pisa, Italy.
Front Pediatr. 2018 Sep 7;6:236. doi: 10.3389/fped.2018.00236. eCollection 2018.
During general anesthesia, while muscle relaxants, latex and antibiotics are normally considered as very common causes of anaphylactic reactions, there are no documented cases of anaphylaxis due to inhalational agents. We report the case of a 6-year-old child scheduled for adenotonsillectomy who had an anaphylactic shock reaction due to Sevoflurane. Several allergic tests were performed to detect the trigger. Drugs used during operation were tested on both patient and three matched controls. While controls were negative, the patient displayed a positive reaction to Sevoflurane. To our knowledge, this is the first published report describing an allergic reaction caused by a volatile anesthetic.
在全身麻醉期间，肌肉松弛剂、乳胶和抗生素通常被认为是过敏反应的常见原因，但目前尚无因吸入性麻醉剂导致过敏反应的文献记载病例。我们报告一例计划行腺样体扁桃体切除术的6岁儿童，其因七氟醚发生过敏性休克反应。进行了多项过敏测试以检测触发因素。对手术中使用的药物在患者和三名匹配对照身上进行了测试。对照结果为阴性，而患者对七氟醚呈阳性反应。据我们所知，这是首篇发表的描述挥发性麻醉剂引起过敏反应的报告。
